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CD34 [QBEnd/10]
Description CD34 (Cluster of differentiation 34) is a single-pass type I transmembrane glycoprotein which primary functions as a cell to cell adhesion factor. As an adhesion factor, CD34 is expressed during stem/progenitor stage of lymphohematopoietic development and possibly mediates the stem cell attachment to the bone marrow, ECM or stromal cells. CD34 is expressed on hematopoietic stem/progenitor cells, endothelial cells, fibroblasts and other stromal components. CD34 is an important marker for quantifying and purifying hematopoietic progenitor/stem cells. It is useful in identification of tumors with endothelial or lymphoid differentiation. In addition, CD34 aids in detection of gastrointestinal stromal tumors. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Cynomolgus Monkey, Rhesus Macaque 
1 ml more info 
14 days 
€361,40 Add to cart -
CD34 [QBEnd/10]
Description CD34 (Cluster of differentiation 34) is a single-pass type I transmembrane glycoprotein which primary functions as a cell to cell adhesion factor. As an adhesion factor, CD34 is expressed during stem/progenitor stage of lymphohematopoietic development and possibly mediates the stem cell attachment to the bone marrow, ECM or stromal cells. CD34 is expressed on hematopoietic stem/progenitor cells, endothelial cells, fibroblasts and other stromal components. CD34 is an important marker for quantifying and purifying hematopoietic progenitor/stem cells. It is useful in identification of tumors with endothelial or lymphoid differentiation. In addition, CD34 aids in detection of gastrointestinal stromal tumors. (Shipping Cost: €200.00) Host Mouse Application Flow Cyt.(0.5-1ug/million cells), Immunocytochemistry (ICC)/IF (0.5-1ug/ml), Immunohistochemistry (IHC) Reactivity Human, Cynomolgus Monkey, Rhesus Macaque
7 ml more info 14 days
€187,20 Add to cart -
CD35 [E11]
Description CD35, also named as erythrocyte complement receptor 1 (CR1), is a member of the complement activation (RCA) family and is located in the ‘cluster RCA’ region of chromosome 1. CD35 mediates cellular binding to particles and immune complexes that have activated complement. CD35 is present on erythrocytes, various leucocytes and renal glomerular podocytes. In addition, plasma contains a soluble form of CR1 (Scr1). CD35 also can be detected on follicular dendritic cells. It is a marker for the diagnosis of follicular dendritic cell sarcoma. This antibody labels dendritic cells in tonsil and spleen and glomerular podocytes in kidney. Abnormal expression of this protein has been associated with follicular dendritic cell tumor, sarcoidosis, gallbladder carcinomas, mesangiocapillary glomerulonephritis, and systemic lupus erythematosus. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Baboon, Cynomolgus Monkey, Rhesus Macaque
1 ml more info 14 days
€361,40 Add to cart -
CD35 [E11]
Description CD35, also named as erythrocyte complement receptor 1 (CR1), is a member of the complement activation (RCA) family and is located in the ‘cluster RCA’ region of chromosome 1. CD35 mediates cellular binding to particles and immune complexes that have activated complement. CD35 is present on erythrocytes, various leucocytes and renal glomerular podocytes. In addition, plasma contains a soluble form of CR1 (Scr1). CD35 also can be detected on follicular dendritic cells. It is a marker for the diagnosis of follicular dendritic cell sarcoma. This antibody labels dendritic cells in tonsil and spleen and glomerular podocytes in kidney. Abnormal expression of this protein has been associated with follicular dendritic cell tumor, sarcoidosis, gallbladder carcinomas, mesangiocapillary glomerulonephritis, and systemic lupus erythematosus. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Baboon, Cynomolgus Monkey, Rhesus Macaque
7 ml more info 14 days
€187,20 Add to cart -
CD35 [MD80R]
Description CD35, also named as erythrocyte complement receptor 1 (CR1), is a member of the complement activation (RCA) family and is located in the ‘cluster RCA’ region of chromosome 1. CD35 mediates cellular binding to particles and immune complexes that have activated complement. CD35 is present on erythrocytes, various leucocytes and renal glomerular podocytes. In addition, plasma contains a soluble form of CR1 (Scr1). CD35 also can be detected on follicular dendritic cells. It is a marker for the diagnosis of follicular dendritic cell sarcoma. This antibody labels dendritic cells in tonsil and spleen and glomerular podocytes in kidney. Abnormal expression of this protein has been associated with follicular dendritic cell tumor, sarcoidosis, gallbladder carcinomas, mesangiocapillary glomerulonephritis, and systemic lupus erythematosus. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€416,00 Add to cart -
CD35 [MD80R]
Description CD35, also named as erythrocyte complement receptor 1 (CR1), is a member of the complement activation (RCA) family and is located in the ‘cluster RCA’ region of chromosome 1. CD35 mediates cellular binding to particles and immune complexes that have activated complement. CD35 is present on erythrocytes, various leucocytes and renal glomerular podocytes. In addition, plasma contains a soluble form of CR1 (Scr1). CD35 also can be detected on follicular dendritic cells. It is a marker for the diagnosis of follicular dendritic cell sarcoma. This antibody labels dendritic cells in tonsil and spleen and glomerular podocytes in kidney. Abnormal expression of this protein has been associated with follicular dendritic cell tumor, sarcoidosis, gallbladder carcinomas, mesangiocapillary glomerulonephritis, and systemic lupus erythematosus. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€214,50 Add to cart -
CD36 [MD172]
Description Recognizes a protein of 80kDa-90kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
CD38 [AT1]
Description CD38, also called ADP-ribosyl cyclase, is a druggable ectoenzyme that uses nicotinamide adenine dinucleotide (NAD) as a substrate to generate second messengers. In particular, it synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. CD38 also has cADPR hydrolase activity. It is preferentially expressed at both early and late stages of B- and T-cell maturation. In normal lymph nodes and tonsils, the antigen is detected mainly on B cells in germinal centers and plasma cells. An antibody to CD38 is helpful in the identification of plasma cells and tumors with plasmablastic differentiation. A prognostic value of CD38 in B-cell chronic lymphocytic leukemia (CLL) has been reported. Expression of CD38 is linked to unmutated IgVH genes and a worse prognosis. CD38 is involved in the generation of adenosine, which is implicated in tumor immune evasion. CD38 mRNA expression in metastatic castration-resistant prostate cancer (mCRPC) was most significantly associa Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€374,40 Add to cart -
CD38 [AT1]
Description CD38, also called ADP-ribosyl cyclase, is a druggable ectoenzyme that uses nicotinamide adenine dinucleotide (NAD) as a substrate to generate second messengers. In particular, it synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. CD38 also has cADPR hydrolase activity. It is preferentially expressed at both early and late stages of B- and T-cell maturation. In normal lymph nodes and tonsils, the antigen is detected mainly on B cells in germinal centers and plasma cells. An antibody to CD38 is helpful in the identification of plasma cells and tumors with plasmablastic differentiation. A prognostic value of CD38 in B-cell chronic lymphocytic leukemia (CLL) has been reported. Expression of CD38 is linked to unmutated IgVH genes and a worse prognosis. CD38 is involved in the generation of adenosine, which is implicated in tumor immune evasion. CD38 mRNA expression in metastatic castration-resistant prostate cancer (mCRPC) was most significantly associa Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
CD3e [C3e/1931]
Description Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunohistochemistry (IHC) Reactivity Human, Chimpanzee
1 ml more info 14 days
€374,40 Add to cart
