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CD34 [QBEnd/10]
Product group: | Primary |
Monoclonal/ Polyclonal: | Monoclonal |
Clone: | QBEnd/10 |
Host: | Mouse |
Isotype: | IgG1 |
Application: | Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) |
Application notes: | 100-300 |
Conjugation Type: | Unconjugated |
Lightchain type: | Kappa |
Reactivity: | Human, Cynomolgus Monkey, Rhesus Macaque |
General notes: | Localization: membrane. |
Buffer: | citrate pH6.0 |
UNSPSC code: | 12352203 |
CD34 (Cluster of differentiation 34) is a single-pass type I transmembrane glycoprotein which primary functions as a cell to cell adhesion factor. As an adhesion factor, CD34 is expressed during stem/progenitor stage of lymphohematopoietic development and possibly mediates the stem cell attachment to the bone marrow, ECM or stromal cells. CD34 is expressed on hematopoietic stem/progenitor cells, endothelial cells, fibroblasts and other stromal components. CD34 is an important marker for quantifying and purifying hematopoietic progenitor/stem cells. It is useful in identification of tumors with endothelial or lymphoid differentiation. In addition, CD34 aids in detection of gastrointestinal stromal tumors. (Shipping Cost: €200.00)
CD34 [QBEnd/10]
CD34 (Cluster of differentiation 34) is a single-pass type I transmembrane glycoprotein which primary functions as a cell to cell adhesion factor. As an adhesion factor, CD34 is expressed during stem/progenitor stage of lymphohematopoietic development and possibly mediates the stem cell attachment to the bone marrow, ECM or stromal cells. CD34 is expressed on hematopoietic stem/progenitor cells, endothelial cells, fibroblasts and other stromal components. CD34 is an important marker for quantifying and purifying hematopoietic progenitor/stem cells. It is useful in identification of tumors with endothelial or lymphoid differentiation. In addition, CD34 aids in detection of gastrointestinal stromal tumors.
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