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CD34 [QBEnd/10]

Product information References Bioinformatics Documents
Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: QBEnd/10
Host: Mouse
Isotype: IgG1
Application: Flow Cyt.(0.5-1ug/million cells), Immunocytochemistry (ICC)/IF (0.5-1ug/ml), Immunohistochemistry (IHC)
Application notes: Prediluted
Conjugation Type: Unconjugated
Lightchain type: Kappa
Reactivity: Human, Cynomolgus Monkey, Rhesus Macaque
General notes: Localization: membrane.
Buffer: citrate pH6.0
UNSPSC code: 12352203

CD34 (Cluster of differentiation 34) is a single-pass type I transmembrane glycoprotein which primary functions as a cell to cell adhesion factor. As an adhesion factor, CD34 is expressed during stem/progenitor stage of lymphohematopoietic development and possibly mediates the stem cell attachment to the bone marrow, ECM or stromal cells. CD34 is expressed on hematopoietic stem/progenitor cells, endothelial cells, fibroblasts and other stromal components. CD34 is an important marker for quantifying and purifying hematopoietic progenitor/stem cells. It is useful in identification of tumors with endothelial or lymphoid differentiation. In addition, CD34 aids in detection of gastrointestinal stromal tumors. (Shipping Cost: €200.00)

CD34 [QBEnd/10]

CD34 (Cluster of differentiation 34) is a single-pass type I transmembrane glycoprotein which primary functions as a cell to cell adhesion factor. As an adhesion factor, CD34 is expressed during stem/progenitor stage of lymphohematopoietic development and possibly mediates the stem cell attachment to the bone marrow, ECM or stromal cells. CD34 is expressed on hematopoietic stem/progenitor cells, endothelial cells, fibroblasts and other stromal components. CD34 is an important marker for quantifying and purifying hematopoietic progenitor/stem cells. It is useful in identification of tumors with endothelial or lymphoid differentiation. In addition, CD34 aids in detection of gastrointestinal stromal tumors.