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Cytokeratin 14 [LL002]
Description Cytokeratin 14 (CK14) is a 50-kDa keratin expressed in abundance in stratified epithelial cells, epidermal cells, basal cells, mesothelial cells, and myoepithelial cells in various tissues including breast and prostate. CK14 is helpful in the identification of breast cancer with basal phenotype. It has been reported that cytokeratin 5/14-positive breast cancers are true basal phenotype confined to BRCA1 tumors. Along with p63 and CK5, CK14 has been a useful marker for cells with basal, squamous and myoepithelial differentiation. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse, Rat -
Cytokeratin 14 [MD187R]
Description Cytokeratin 14 (CK14) is a 50-kDa keratin expressed in abundance in stratified epithelial cells, epidermal cells, basal cells, mesothelial cells, and myoepithelial cells in various tissues including breast and prostate. CK14 is helpful in the identification of breast cancer with basal phenotype. It has been reported that cytokeratin 5/14-positive breast cancers are true basal phenotype confined to BRCA1 tumors. Along with p63 and CK5, CK14 has been a useful marker for cells with basal, squamous and myoepithelial differentiation. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat -
Cytokeratin 14 [MD187R]
Description Cytokeratin 14 (CK14) is a 50-kDa keratin expressed in abundance in stratified epithelial cells, epidermal cells, basal cells, mesothelial cells, and myoepithelial cells in various tissues including breast and prostate. CK14 is helpful in the identification of breast cancer with basal phenotype. It has been reported that cytokeratin 5/14-positive breast cancers are true basal phenotype confined to BRCA1 tumors. Along with p63 and CK5, CK14 has been a useful marker for cells with basal, squamous and myoepithelial differentiation. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat -
Cytokeratin 15 [MD90R]
Description Cytokeratin 15 (CK15) is involved in the development of stratified epithelia from one-layered polar epithelia and continues to be expressed in several adult epithelial tissues. It labels the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Although CK15 in normal hair follicles was virtually absent from hair bulbs, it was expressed by a subset of keratinocytes in the outer root sheath. In human conjunctival epithelium, strong expression of CK15 was observed in basal cells, whereas Cytokeratin 19 was expressed in both basal and suprabasal layers. CK15 may be used to differentiate primary from metastatic skin cancer. It may be a useful stem cell marker for hair follicle and breast epithelium. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
Cytokeratin 15 [MD90R]
Description Cytokeratin 15 (CK15) is involved in the development of stratified epithelia from one-layered polar epithelia and continues to be expressed in several adult epithelial tissues. It labels the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Although CK15 in normal hair follicles was virtually absent from hair bulbs, it was expressed by a subset of keratinocytes in the outer root sheath. In human conjunctival epithelium, strong expression of CK15 was observed in basal cells, whereas Cytokeratin 19 was expressed in both basal and suprabasal layers. CK15 may be used to differentiate primary from metastatic skin cancer. It may be a useful stem cell marker for hair follicle and breast epithelium. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
Cytokeratin 16 [MD91R]
Description Cytokeratin 16 (CK16), also known as keratin 16, is a member of the large intermediate filament protein family that form the cytoskeleton. This family is subdivided into acidic (type I) and basic (type II) cytokeratins, but are obligatory heteropolymers, where expression of at least one member of each subfamily is required for filament formation. CK16 is classified as type I, pairing with type II cytokeratin 6. In normal tissues, CK16 is constitutively expressed at low levels in the palmar and plantar epidermis, tongue, oral mucosa, and hair follicles. Studies have proposed a modulatory role of CK16 in cell proliferation, suggesting its utility as a marker for proliferation. Rapid induction of CK16 expression near the edge of wounds, up regulation in response to epidermal growth factor stimulus, and overexpression in hyperproliferative disorders, including psoriasis and chronic contact dermatitis, support this assertion. In psoriasis, the severity of disease is correlated with the amou Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
Cytokeratin 17 [E3]
Description CK17 is an intermediate filament protein expressed in the basal cells and myoepithelial cells of complex epithelia, including glandular epithelium with myoepithelial component, transitional and pseudostratified epithelia. CK17 is a marker in the identification of breast cancer with basal phenotype. Squamous cell carcinoma is also labeled by CK17 antibody. Antibody against CK17 may be an aid in distinguishing cholangiocarcinoma (CK17+) from hepatocellular carcinoma (CK17-). In combination with MUC1, CK17 antibody has been found to be useful in distinguishing pancreatobiliary adenocarcinoma (CK17+) from extrapancreatobiliary nonmucinous adenocarcinoma (CK17-). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Rat, Bovine, Goat,Pig (Porcine) -
Cytokeratin 17 [E3]
Description CK17 is an intermediate filament protein expressed in the basal cells and myoepithelial cells of complex epithelia, including glandular epithelium with myoepithelial component, transitional and pseudostratified epithelia. CK17 is a marker in the identification of breast cancer with basal phenotype. Squamous cell carcinoma is also labeled by CK17 antibody. Antibody against CK17 may be an aid in distinguishing cholangiocarcinoma (CK17+) from hepatocellular carcinoma (CK17-). In combination with MUC1, CK17 antibody has been found to be useful in distinguishing pancreatobiliary adenocarcinoma (CK17+) from extrapancreatobiliary nonmucinous adenocarcinoma (CK17-). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Rat, Bovine, Goat,Pig (Porcine) -
Cytokeratin 18 [DC10]
Description Cytokeratin 18 (CK18) is intermediate filament phosphoglycoprotein that is expressed in simple and glandular and transitional epithelial cells but not in stratified epithelial cells. CK18 is often co-expressed with CK8. CK8/18 is the major keratin pair in simple-type epithelia. Adenocarcinomas originated from simple and glandular epithelium showed CK18 positive staining. In squamous carcinoma, poorly differentiated tumor cells show CK18 reactivity. Loss of CK 18 expression is associated with progression of breast carcinoma. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human -
Cytokeratin 18 [DC10]
Description Cytokeratin 18 (CK18) is intermediate filament phosphoglycoprotein that is expressed in simple and glandular and transitional epithelial cells but not in stratified epithelial cells. CK18 is often co-expressed with CK8. CK8/18 is the major keratin pair in simple-type epithelia. Adenocarcinomas originated from simple and glandular epithelium showed CK18 positive staining. In squamous carcinoma, poorly differentiated tumor cells show CK18 reactivity. Loss of CK 18 expression is associated with progression of breast carcinoma. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human