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Cytokeratin 14 [LL002]

Product information References Bioinformatics Documents
Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: LL002
Host: Mouse
Isotype: IgG3
Application: Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC)
Application notes: Prediluted
Conjugation Type: Unconjugated
Reactivity: Human, Mouse, Rat
General notes: Localization: cytoplasm.
Buffer: citrate pH6.0
UNSPSC code: 12352203

Cytokeratin 14 (CK14) is a 50-kDa keratin expressed in abundance in stratified epithelial cells, epidermal cells, basal cells, mesothelial cells, and myoepithelial cells in various tissues including breast and prostate. CK14 is helpful in the identification of breast cancer with basal phenotype. It has been reported that cytokeratin 5/14-positive breast cancers are true basal phenotype confined to BRCA1 tumors. Along with p63 and CK5, CK14 has been a useful marker for cells with basal, squamous and myoepithelial differentiation. (Shipping Cost: €200.00)

Cytokeratin 14 [LL002]

Cytokeratin 14 (CK14) is a 50-kDa keratin expressed in abundance in stratified epithelial cells, epidermal cells, basal cells, mesothelial cells, and myoepithelial cells in various tissues including breast and prostate. CK14 is helpful in the identification of breast cancer with basal phenotype. It has been reported that cytokeratin 5/14-positive breast cancers are true basal phenotype confined to BRCA1 tumors. Along with p63 and CK5, CK14 has been a useful marker for cells with basal, squamous and myoepithelial differentiation.