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Cytokeratin 17 [E3]
| Product group: | Primary |
| Monoclonal/ Polyclonal: | Monoclonal |
| Clone: | E3 |
| Host: | Mouse |
| Isotype: | IgG2b |
| Application: | Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) |
| Application notes: | 50-200 |
| Conjugation Type: | Unconjugated |
| Lightchain type: | Kappa |
| Reactivity: | Human, Rat, Bovine, Goat,Pig (Porcine) |
| General notes: | Localization: cytoplasm. |
| Buffer: | citrate pH6.0 |
| UNSPSC code: | 12352203 |
CK17 is an intermediate filament protein expressed in the basal cells and myoepithelial cells of complex epithelia, including glandular epithelium with myoepithelial component, transitional and pseudostratified epithelia. CK17 is a marker in the identification of breast cancer with basal phenotype. Squamous cell carcinoma is also labeled by CK17 antibody. Antibody against CK17 may be an aid in distinguishing cholangiocarcinoma (CK17+) from hepatocellular carcinoma (CK17-). In combination with MUC1, CK17 antibody has been found to be useful in distinguishing pancreatobiliary adenocarcinoma (CK17+) from extrapancreatobiliary nonmucinous adenocarcinoma (CK17-). (Shipping Cost: €200.00)
Cytokeratin 17 [E3]
CK17 is an intermediate filament protein expressed in the basal cells and myoepithelial cells of complex epithelia, including glandular epithelium with myoepithelial component, transitional and pseudostratified epithelia. CK17 is a marker in the identification of breast cancer with basal phenotype. Squamous cell carcinoma is also labeled by CK17 antibody. Antibody against CK17 may be an aid in distinguishing cholangiocarcinoma (CK17+) from hepatocellular carcinoma (CK17-). In combination with MUC1, CK17 antibody has been found to be useful in distinguishing pancreatobiliary adenocarcinoma (CK17+) from extrapancreatobiliary nonmucinous adenocarcinoma (CK17-).
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