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FLK2/Flt3/CD135 [MD103]
Description This antibody reacts with CD135, also known as Flk2/Flt3. A member of the tyrosine kinase receptor family, this 135-150 kDa molecule is expressed by primitive progenitor cells in fetal liver and adult bone marrow. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunohistochemistry on paraffin sections (IHC-P), Western Blot (WB) Reactivity Human 
1 ml more info 
14 days 
€416,00 Add to cart -
FLK2/Flt3/CD135 [MD103]
Description This antibody reacts with CD135, also known as Flk2/Flt3. A member of the tyrosine kinase receptor family, this 135-150 kDa molecule is expressed by primitive progenitor cells in fetal liver and adult bone marrow. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunohistochemistry on paraffin sections (IHC-P), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€201,50 Add to cart -
FOXA1/HNF3A [FOXA1/1512]
Description The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. FOXA1 has been identified as a hepatocyte enriched factor required for the expression of transthyretin and α1-antitrypsin. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER)-positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€374,40 Add to cart -
FOXA1/HNF3A [FOXA1/1512]
Description The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. FOXA1 has been identified as a hepatocyte enriched factor required for the expression of transthyretin and α1-antitrypsin. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER)-positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
FOXG1/BF-1 Polyclonal
Description The winged-helix transcriptional repressor (WH) BF-1 gene encodes brain factor 1 (BF-1), also known as foxg1, and is essential for the proliferation of progenitor cells in the cerebral cortex and influences regional patterning in the mammalian telencephalon. WH proteins are a family of putative transcriptional regulators with diverse roles in development, and are characterized by a highly conserved DNA binding structure, the WH domain. BF-1 plays a critical role in the development of the cerebral hemispheres of the brain and targeted disruption of the gene leads to severe defects in the development of telencephalic structures, such as the cerebral cortex and basal ganglia. The loss of BF-1 results in an accelerated rate of neuronal differentiation and the shortening of the neurogenetic period in the embryonic cerebral cortex. BF-1 is expressed by E8.5 in telencephalic progenitors. It may also regulate the response of cerebral cortical progenitors to environmental cues. (Shipping Cost: Host Rabbit Application Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat 
1 ml more info 14 days
€494,00 Add to cart -
FOXG1/BF-1 Polyclonal
Description The winged-helix transcriptional repressor (WH) BF-1 gene encodes brain factor 1 (BF-1), also known as foxg1, and is essential for the proliferation of progenitor cells in the cerebral cortex and influences regional patterning in the mammalian telencephalon. WH proteins are a family of putative transcriptional regulators with diverse roles in development, and are characterized by a highly conserved DNA binding structure, the WH domain. BF-1 plays a critical role in the development of the cerebral hemispheres of the brain and targeted disruption of the gene leads to severe defects in the development of telencephalic structures, such as the cerebral cortex and basal ganglia. The loss of BF-1 results in an accelerated rate of neuronal differentiation and the shortening of the neurogenetic period in the embryonic cerebral cortex. BF-1 is expressed by E8.5 in telencephalic progenitors. It may also regulate the response of cerebral cortical progenitors to environmental cues. (Shipping Cost: Host Rabbit Application Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat
7 ml more info 14 days
€254,80 Add to cart -
FOXL1 Polyclonal
Description Forkhead box protein L1s or FKHL11, is encoded by the FOXL1 gene in human. FOXL1 protein belongs to the forehead box (Fox) family of transcription factors characterized by a common DNA-binding domain (the forkhead box). FOXL1 is involved in regulating the proliferation of gastrointestinal epithelial cells. Loss of Foxl1 leads to distorted architecture of the stomach and small intestine in mice due to a markedly increased epithelial proliferation. Foxl1 knockout is correlated with an enhanced Wnt/β-catenin pathway activation as evidenced by increased β-catenin nuclear localization. FOXL1 expression is down-regulated in the majority of human clear cell renal cell carcinoma (ccRCC), at both mRNA and protein levels. FOXL1 expression inversely correlates with the aggressive phenotype of ccRCC and the survival outcome of patients. (Shipping Cost: €200.00) Host Rabbit Application ELISA, Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€494,00 Add to cart -
FOXP1 [MD189R]
Description The FOXP1 protein belongs to a functionally diverse family of winged-helix or forkhead transcription factors that have diverse roles in cellular proliferation, differentiation, and neoplastic transformation. The FOXP1 gene has been mapped to chromosome 3p14.1, a region that commonly shows loss of heterozygosity in a wide range of tumors and is reported to contain a tumor suppressor gene(s). The FOXP1 protein is widely expressed in normal human tissues. It labels activated B cells in the mantle zone and germinal center of lymphoid tissues. In lymphoid malignancies, FOXP1 protein expression may be found in diffuse large B-cell lymphomas and extranodal marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue (MALT). Strong expression of FOXP1 is associated with poor disease-free survival and transformation to diffuse large Bcell lymphomas. Recently, studies suggested a role of FOXP1 in the regulation of ER expression. FOXP1 expression is correlated with ER expression and improv Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€442,00 Add to cart -
FOXP1 [MD189R]
Description The FOXP1 protein belongs to a functionally diverse family of winged-helix or forkhead transcription factors that have diverse roles in cellular proliferation, differentiation, and neoplastic transformation. The FOXP1 gene has been mapped to chromosome 3p14.1, a region that commonly shows loss of heterozygosity in a wide range of tumors and is reported to contain a tumor suppressor gene(s). The FOXP1 protein is widely expressed in normal human tissues. It labels activated B cells in the mantle zone and germinal center of lymphoid tissues. In lymphoid malignancies, FOXP1 protein expression may be found in diffuse large B-cell lymphomas and extranodal marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue (MALT). Strong expression of FOXP1 is associated with poor disease-free survival and transformation to diffuse large Bcell lymphomas. Recently, studies suggested a role of FOXP1 in the regulation of ER expression. FOXP1 expression is correlated with ER expression and improv Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€234,00 Add to cart -
FOXP3/Scurfin [EP340]
Description Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€494,00 Add to cart
