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FOXA1/HNF3A [FOXA1/1512]

Product information References Bioinformatics Documents
Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: FOXA1/1512
Host: Mouse
Isotype: IgG1
Application: Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application notes: 50-200
Conjugation Type: Unconjugated
Reactivity: Human
General notes: Localization: nucleus.
Buffer: Tris EDTA pH9.0
UNSPSC code: 12352203

The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. FOXA1 has been identified as a hepatocyte enriched factor required for the expression of transthyretin and α1-antitrypsin. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER)-positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis. (Shipping Cost: €200.00)

FOXA1/HNF3A [FOXA1/1512]

The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. FOXA1 has been identified as a hepatocyte enriched factor required for the expression of transthyretin and α1-antitrypsin. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER)-positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis.