You are here
-
CD2 [MD150R]
Description T-cell surface antigen CD2 (CD2) is a T-cell specific surface glycoprotein that is critically important for mediating adherence of T cells to antigen-presenting cells or target cells. It interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is involved in triggering T-cells, and the cytoplasmic domain is involved in signaling. CD2 is a pan T-cell marker. CD2 antibody labels T-cell, thymocytes and natural killer (NK) cells. CD2 is absent in a small subset of T cells. CD2 antibody is useful for identification of precursor and mature T-cell lymphomas. Aberrant loss of CD2 in T-cell lymphomas may help to distinguish them from reactive T-cell proliferations. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
CD20 (B Cell) [L26]
Description CD20 is a transmembrane phosphprotein which functions as a calcium-permeable cation channel involved in B cell activation, proliferation and differentiation. It is expressed on both normal and malignant B cells. The expression of CD20 is observed in all mature B lymphocytes but lost in terminal differentiated plasma cells. CD20 is one of the most important markers for B cell. It labels almost all mature B cell lymphoma, half of lymphoblastic lymphoma/leukemia and Reed-Sternberg cells in Hodgkin's disease. It has also been used to monitor down regulation of CD20 in patient treated with Rituximab for B cell lymphoma. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human -
CD20 (B Cell) [L26]
Description CD20 is a transmembrane phosphprotein which functions as a calcium-permeable cation channel involved in B cell activation, proliferation and differentiation. It is expressed on both normal and malignant B cells. The expression of CD20 is observed in all mature B lymphocytes but lost in terminal differentiated plasma cells. CD20 is one of the most important markers for B cell. It labels almost all mature B cell lymphoma, half of lymphoblastic lymphoma/leukemia and Reed-Sternberg cells in Hodgkin's disease. It has also been used to monitor down regulation of CD20 in patient treated with Rituximab for B cell lymphoma. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human -
CD205/LY75/gp200 [SPM487]
Description CD205, also named DEC-205, belongs to the macrophage mannose receptor family of C-type lectin endocytic receptors. CD205 is predominantly expressed by the thymic cortical epithelium and by dendritic cells (DC), but can also be detected at low levels in T and B lymphocytes and several other epithelial cell types. CD205 is a novel thymic epithelial marker that is important for the positive selection process of thymocytes. It is a sensitive and specific marker for thymoma, while the sensitivity to thymic carcinoma is lower than CD5 and CD117. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Horse -
CD205/LY75/gp200 [SPM487]
Description CD205, also named DEC-205, belongs to the macrophage mannose receptor family of C-type lectin endocytic receptors. CD205 is predominantly expressed by the thymic cortical epithelium and by dendritic cells (DC), but can also be detected at low levels in T and B lymphocytes and several other epithelial cell types. CD205 is a novel thymic epithelial marker that is important for the positive selection process of thymocytes. It is a sensitive and specific marker for thymoma, while the sensitivity to thymic carcinoma is lower than CD5 and CD117. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Horse -
CD21 [CR2/3124R]
Description CD21 is a single-pass type 2 transmembrane protein that serves as the complement receptor for C3d and the Epstein-Barr virus. CD21 labels follicular dendritic cells and mature B cells particularly in marginal and mantle zone of lymphoid tissues. It is a useful marker to identify neoplasms derived from follicular dendritic cells. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human -
CD21 [CR2/3124R]
Description CD21 is a single-pass type 2 transmembrane protein that serves as the complement receptor for C3d and the Epstein-Barr virus. CD21 labels follicular dendritic cells and mature B cells particularly in marginal and mantle zone of lymphoid tissues. It is a useful marker to identify neoplasms derived from follicular dendritic cells. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human -
CD21 [EP64]
Description CD21 is a single-pass type 2 transmembrane protein that serves as the complement receptor for C3d and the Epstein-Barr virus. CD21 labels follicular dendritic cells and mature B cells particularly in marginal and mantle zone of lymphoid tissues. It is a useful marker to identify neoplasms derived from follicular dendritic cells. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
CD21 [EP64]
Description CD21 is a single-pass type 2 transmembrane protein that serves as the complement receptor for C3d and the Epstein-Barr virus. CD21 labels follicular dendritic cells and mature B cells particularly in marginal and mantle zone of lymphoid tissues. It is a useful marker to identify neoplasms derived from follicular dendritic cells. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
CD22 [BLCAM/1795]
Description CD22 is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140kD. It is expressed in both the cytoplasm and cell membrane of B lymphocytes. CD22 antigen appears early in B cell lymphocyte differentiation at approximately the same stage as the CD19 antigen. Unlike other B cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-). CD22 is also strongly expressed in hairy cell leukemia. There are two different isoforms of CD22. It exists predominantly as a monomer of the beta isoform but can also be found as a heterodimer composed of the beta isoform and a second, shorter isoform (CD22 alpha). (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human