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CD205/LY75/gp200 [SPM487]
Product group: | Primary |
Monoclonal/ Polyclonal: | Monoclonal |
Clone: | SPM487 |
Host: | Mouse |
Isotype: | IgG2b |
Application: | Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) |
Application notes: | Prediluted |
Conjugation Type: | Unconjugated |
Lightchain type: | Kappa |
Reactivity: | Human, Horse |
General notes: | Localization: membrane, cytoplasm. |
Buffer: | citrate pH6.0 or EDTA pH8.0 |
UNSPSC code: | 12352203 |
CD205, also named DEC-205, belongs to the macrophage mannose receptor family of C-type lectin endocytic receptors. CD205 is predominantly expressed by the thymic cortical epithelium and by dendritic cells (DC), but can also be detected at low levels in T and B lymphocytes and several other epithelial cell types. CD205 is a novel thymic epithelial marker that is important for the positive selection process of thymocytes. It is a sensitive and specific marker for thymoma, while the sensitivity to thymic carcinoma is lower than CD5 and CD117. (Shipping Cost: €200.00)
CD205/LY75/gp200 [SPM487]
CD205, also named DEC-205, belongs to the macrophage mannose receptor family of C-type lectin endocytic receptors. CD205 is predominantly expressed by the thymic cortical epithelium and by dendritic cells (DC), but can also be detected at low levels in T and B lymphocytes and several other epithelial cell types. CD205 is a novel thymic epithelial marker that is important for the positive selection process of thymocytes. It is a sensitive and specific marker for thymoma, while the sensitivity to thymic carcinoma is lower than CD5 and CD117.
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