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CD20 (B Cell) [L26]
| Product group: | Primary |
| Monoclonal/ Polyclonal: | Monoclonal |
| Clone: | L26 |
| Host: | Mouse |
| Isotype: | IgG2a |
| Application: | Immunohistochemistry (IHC) |
| Application notes: | Prediluted |
| Conjugation Type: | Unconjugated |
| Lightchain type: | Kappa |
| Reactivity: | Human |
| General notes: | Localization: membrane, cytoplasm. |
| Buffer: | EDTA pH8.0 |
| UNSPSC code: | 12352203 |
CD20 is a transmembrane phosphprotein which functions as a calcium-permeable cation channel involved in B cell activation, proliferation and differentiation. It is expressed on both normal and malignant B cells. The expression of CD20 is observed in all mature B lymphocytes but lost in terminal differentiated plasma cells. CD20 is one of the most important markers for B cell. It labels almost all mature B cell lymphoma, half of lymphoblastic lymphoma/leukemia and Reed-Sternberg cells in Hodgkin's disease. It has also been used to monitor down regulation of CD20 in patient treated with Rituximab for B cell lymphoma. (Shipping Cost: €200.00)
CD20 (B Cell) [L26]
CD20 is a transmembrane phosphprotein which functions as a calcium-permeable cation channel involved in B cell activation, proliferation and differentiation. It is expressed on both normal and malignant B cells. The expression of CD20 is observed in all mature B lymphocytes but lost in terminal differentiated plasma cells. CD20 is one of the most important markers for B cell. It labels almost all mature B cell lymphoma, half of lymphoblastic lymphoma/leukemia and Reed-Sternberg cells in Hodgkin's disease. It has also been used to monitor down regulation of CD20 in patient treated with Rituximab for B cell lymphoma.
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