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Chromogranin A [LK2H10]
Description Chromogranin A (CgA) is an 86 kDa protein that is the major member of the granin family of acidic secretory glycoproteins located in neurosecretory granules of neuroendocrine cells. Chromogranin A showed broad expression in endocrine tissues including pituitary, adrenal medulla, thyroid, pancreatic islets and gastrointestinal tract. Chromogranin A represents the single most specific marker of neuroendocrine differentiation in general use. It is useful for identification of neuroendocrine tumors. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Monkey,Pig (Porcine), Mouse, Rat 
1 ml more info 
14 days 
€361,40 Add to cart -
Collagen I [COL1]
Description The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. This clone reacts collagen I. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat, Bovine,Pig (Porcine), Cat, Dog
1 ml more info 14 days
€401,70 Add to cart -
Collagen I [COL1]
Description The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. This clone reacts collagen I. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat, Bovine,Pig (Porcine), Cat, Dog
7 ml more info 14 days
€187,20 Add to cart -
Cytokeratin 17 [E3]
Description CK17 is an intermediate filament protein expressed in the basal cells and myoepithelial cells of complex epithelia, including glandular epithelium with myoepithelial component, transitional and pseudostratified epithelia. CK17 is a marker in the identification of breast cancer with basal phenotype. Squamous cell carcinoma is also labeled by CK17 antibody. Antibody against CK17 may be an aid in distinguishing cholangiocarcinoma (CK17+) from hepatocellular carcinoma (CK17-). In combination with MUC1, CK17 antibody has been found to be useful in distinguishing pancreatobiliary adenocarcinoma (CK17+) from extrapancreatobiliary nonmucinous adenocarcinoma (CK17-). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Rat, Bovine, Goat,Pig (Porcine)
1 ml more info 14 days
€361,40 Add to cart -
Cytokeratin 17 [E3]
Description CK17 is an intermediate filament protein expressed in the basal cells and myoepithelial cells of complex epithelia, including glandular epithelium with myoepithelial component, transitional and pseudostratified epithelia. CK17 is a marker in the identification of breast cancer with basal phenotype. Squamous cell carcinoma is also labeled by CK17 antibody. Antibody against CK17 may be an aid in distinguishing cholangiocarcinoma (CK17+) from hepatocellular carcinoma (CK17-). In combination with MUC1, CK17 antibody has been found to be useful in distinguishing pancreatobiliary adenocarcinoma (CK17+) from extrapancreatobiliary nonmucinous adenocarcinoma (CK17-). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Rat, Bovine, Goat,Pig (Porcine)
7 ml more info 14 days
€187,20 Add to cart -
Cytokeratin 5/8 [C-50]
Description It reacts with keratin 5 (58kDa) and keratin 8 (52.5kDa). Simple epithelia express cytokeratin 8 in combination with 18. On the other hand, basal cells of stratified epithelia express cytokeratin 5 paired with 14. This antibody therefore, reacts with a wide range of epithelia and their carcinomas. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human,Pig (Porcine), Mouse, Rat, Hamster, Bovine, Dog (Canine), Sheep
1 ml more info 14 days
€361,40 Add to cart -
ER-beta [ERb455]
Description Isoform beta-1 is expressed in testis and ovary, and at a lower level in heart, brain, placenta, liver, skeletal muscle, spleen, thymus, prostate, colon, bone marrow, mammary gland and uterus. Also found in uterine bone, breast, and ovarian tumor cell lines, but not in colon and liver tumors. Isoform beta-2 is expressed in spleen, thymus, testis and ovary and at a lower level in skeletal muscle, prostate, colon, small intestine, leukocytes, bone marrow, mammary gland and uterus. Isoform beta-3 is found in testis. Isoform beta-4 is expressed in testis, and at a lower level in spleen, thymus, ovary, mammary gland and uterus. Isoform beta-5 is expressed in testis, placenta, skeletal muscle, spleen and leukocytes, and at a lower level in heart, lung, liver, kidney, pancreas, thymus, prostate, colon, small intestine, bone marrow, mammary gland and uterus. Not expressed in brain. Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of r Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Monkey, Mouse, Rat,Pig (Porcine), Horse, Sheep
1 ml more info 14 days
€361,40 Add to cart -
ER-beta [ERb455]
Description Isoform beta-1 is expressed in testis and ovary, and at a lower level in heart, brain, placenta, liver, skeletal muscle, spleen, thymus, prostate, colon, bone marrow, mammary gland and uterus. Also found in uterine bone, breast, and ovarian tumor cell lines, but not in colon and liver tumors. Isoform beta-2 is expressed in spleen, thymus, testis and ovary and at a lower level in skeletal muscle, prostate, colon, small intestine, leukocytes, bone marrow, mammary gland and uterus. Isoform beta-3 is found in testis. Isoform beta-4 is expressed in testis, and at a lower level in spleen, thymus, ovary, mammary gland and uterus. Isoform beta-5 is expressed in testis, placenta, skeletal muscle, spleen and leukocytes, and at a lower level in heart, lung, liver, kidney, pancreas, thymus, prostate, colon, small intestine, bone marrow, mammary gland and uterus. Not expressed in brain. Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of r Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Monkey, Mouse, Rat,Pig (Porcine), Horse, Sheep
7 ml more info 14 days
€187,20 Add to cart -
HLA-DQ (MHC II) [SPV-L3]
Description Recognizes a DQ antigen, which is a dimer of 60kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.ĀThis MAb strongly blocks cytotoxicity activity of T4-positive cytotoxic T cell clones. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human,Pig (Porcine)
1 ml more info 14 days
€361,40 Add to cart -
Insulin [2D11-H5]
Description Insulin is a hormone that regulates glucose homeostasis. It increases cell permeability to monosaccharides, amino acids and fatty acids, and it accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. It is synthesized in the beta cell of the pancreas. The antibody labels both normal and neoplastic insulin-producing cells. It is useful in identifying insulinoma. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse, Bovine,Pig (Porcine)
1 ml more info 14 days
€361,40 Add to cart
