You are here
-
CD47/IAP (Integrin Associated Protein) [CD47/2937]
Description This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse -
CD48 [MD134]
Description CD48 (BLAST1) is an activation-associated, glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein expressed primarily in mitogen-stimulated human lymphocytes. CD48 is expressed on T cells, B cells, thymocytes and splenocytes. Both normal and malignant white blood cells express CD48 on their membrane surface, but greater than 95% of CD34+ hematopoietic stem cells do not express CD48. CD48 is expressed at higher levels on human Burkitt's lymphoma cell lines, Raji and most acute myeloid leukemia cells with phenotype CD34-/CD13+/CD33+. Although much remains to be elucidated, CD48 is a critical marker for human immunity, and will most likely be of use in the treatment of many diseases like hematopoietic tumors, autoimmunity, allergy and chronic inflammatory diseases. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP) Reactivity Human -
CD5 [C5/473&CD5/54/F6]
Description CD5 (Lymphocyte antigen T1/Leu-1) is a transmembrane glycoprotein which has been implicated as a receptor in the regulation of T-cell proliferation. CD5 antibody labels a variety of T lymphocytes, mantle zone lymphocytes and a small subset of B lymphocytes. In tumors, CD5 is expressed on T-cell malignancies, Bcell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL), and mantle-cell lymphoma. It is a useful diagnostic tool for these tumors. In addition, anti-CD5 is helpful in diagnosis of thymic carcinoma (CD5 positive). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Rabbit, Rat, Bovine -
CD5 [C5/473&CD5/54/F6]
Description CD5 (Lymphocyte antigen T1/Leu-1) is a transmembrane glycoprotein which has been implicated as a receptor in the regulation of T-cell proliferation. CD5 antibody labels a variety of T lymphocytes, mantle zone lymphocytes and a small subset of B lymphocytes. In tumors, CD5 is expressed on T-cell malignancies, Bcell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL), and mantle-cell lymphoma. It is a useful diagnostic tool for these tumors. In addition, anti-CD5 is helpful in diagnosis of thymic carcinoma (CD5 positive). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Rabbit, Rat, Bovine -
CD5 [EP77]
Description CD5 (Lymphocyte antigen T1/Leu-1) is a transmembrane glycoprotein which has been implicated as a receptor in the regulation of T-cell proliferation. CD5 antibody labels a variety of T lymphocytes, mantle zone lymphocytes and a small subset of B lymphocytes. In tumors, CD5 is expressed on T-cell malignancies, Bcell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL), and mantle-cell lymphoma. It is a useful diagnostic tool for these tumors. In addition, anti-CD5 is helpful in diagnosis of thymic carcinoma (CD5 positive). (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
CD5 [EP77]
Description CD5 (Lymphocyte antigen T1/Leu-1) is a transmembrane glycoprotein which has been implicated as a receptor in the regulation of T-cell proliferation. CD5 antibody labels a variety of T lymphocytes, mantle zone lymphocytes and a small subset of B lymphocytes. In tumors, CD5 is expressed on T-cell malignancies, Bcell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL), and mantle-cell lymphoma. It is a useful diagnostic tool for these tumors. In addition, anti-CD5 is helpful in diagnosis of thymic carcinoma (CD5 positive). (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
CD50 (ICAM-3) [186-2G9]
Description CD50 (ICAM-3) is a leukocyte-specific surface receptor involved in primary immune responses. It belongs to the immunoglobulin gene superfamily (Igsf). CD50 is constitutively expressed on human leukocytes, such as T and B lymphocytes, monocytes and neutrophils, and localizes to the rear of polarized leukocytes and clusters with the ezrin-radixin-moesin (ERM) proteins moesin and ezrin. These ERM proteins link CD50 to the actin cytoskeleton. It recognizes the Beta 2-integrin leukocyte function associated molecule-1 (LFA-1) as a receptor, moreover it also functions as a ligand for LFA-1, Mac-1 (CD11b/CD8), adb2 integrins, and the Dendritic Cell-Specific ICAM-3-Grabbing Non Integrin (DC-SIGN) C-type lectin. CD50 mediates a plethora of immunologically relevant homotypic and heterotypic intercellular interactions, such as leukocyte recruitment during migration, removal of apoptotic cells and lymphocyte interactions with antigen-presenting cells. Importantly, CD50 is involved in the interactio Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human -
CD50 (ICAM-3) [186-2G9]
Description CD50 (ICAM-3) is a leukocyte-specific surface receptor involved in primary immune responses. It belongs to the immunoglobulin gene superfamily (Igsf). CD50 is constitutively expressed on human leukocytes, such as T and B lymphocytes, monocytes and neutrophils, and localizes to the rear of polarized leukocytes and clusters with the ezrin-radixin-moesin (ERM) proteins moesin and ezrin. These ERM proteins link CD50 to the actin cytoskeleton. It recognizes the Beta 2-integrin leukocyte function associated molecule-1 (LFA-1) as a receptor, moreover it also functions as a ligand for LFA-1, Mac-1 (CD11b/CD8), adb2 integrins, and the Dendritic Cell-Specific ICAM-3-Grabbing Non Integrin (DC-SIGN) C-type lectin. CD50 mediates a plethora of immunologically relevant homotypic and heterotypic intercellular interactions, such as leukocyte recruitment during migration, removal of apoptotic cells and lymphocyte interactions with antigen-presenting cells. Importantly, CD50 is involved in the interactio Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human -
CD52 [CD52/2276R]
Description CD52 is a small (25-29 kDa), heavily glycosylated peptide that is bound to the cell surface membrane by a GPI link. Also known as CAMPATH-1, CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable. CD52 is an ideal target for therapeutic agents involved in the treatment of B cell malignancies and autoimmune diseases including rheumatoid arthritis and multiple sclerosis. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human, Monkey -
CD52 [CD52/2276R]
Description CD52 is a small (25-29 kDa), heavily glycosylated peptide that is bound to the cell surface membrane by a GPI link. Also known as CAMPATH-1, CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable. CD52 is an ideal target for therapeutic agents involved in the treatment of B cell malignancies and autoimmune diseases including rheumatoid arthritis and multiple sclerosis. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human, Monkey