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CD185/CXCR5 [MD147R]
Description CD185 is a G protein-coupled receptor belonging to the chemokine receptor subfamily. Upon binding of its ligand, the chemokine CXCL13, CXCR5 initiates multiple intracellular signaling pathways that regulate cell proliferation, survival, and migration. CXCR5 is expressed in both mature B cells and follicular helper T cells, and respond to CXCL13 gradient to control lymphocyte migration towards secondary lymphoid tissues. CXCR5 has also been shown to be highly expressed in primary breast tumors, in correlation with their propensity to grow and metastasize. CXCR5 binds B-lymphocyte chemoattractant (BLC) and is involved in B-cell homing to follicles in lymph nodes and spleen. Two isoforms are produced by alternative splicing. CXCR5 expression has been reported in human blood and salivary gland and in animal lymphatic organs, blood, bone marrow, brain, liver, lymph node, skin, spleen, stomach, and tonsil. ESTs have been isolated from human brain, germ cell, lung, lymph, pancreas, skin, stom Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human 
1 ml more info 
14 days 
€455,00 Add to cart -
CD194/CCR4 Polyclonal
Description Predominantly expressed in the thymus, in peripheral blood leukocytes, including T-cells, mostly CD4+ cells, and basophils, and in platelets; at lower levels, in the spleen and in monocytes. Detected also in macrophages, IL-2-activated natural killer cells and skin-homing memory T-cells, mostly the ones expressing the cutaneous lymphocyte antigen (CLA). Expressed in brain microvascular and coronary artery endothelial cells. High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. (Shipping Cost: €200.00) Host Rabbit Application ELISA, Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human 
1 ml more info 14 days
€401,70 Add to cart -
CD197/CCR7 [CFO3]
Description CD197 (CCR7) is a member of the G protein coupled receptor family (subfamily : chemokine). This receptor was identified as a gene induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CD197 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. It is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€455,00 Add to cart -
CD1a [O10]
Description Cluster of Differentiation 1a (CD1a) is part of a family of major histocompatibility complex (MHC) antigen-like glycoproteins that associate with beta-2-microglobulin. CD1a binds self and non-self lipid and glycolipid antigens, presenting them to T-cell receptors on natural killer T-cells. CD1a antibody labels cortical thymocytes, Langerhans’ cells and dendritic cells. It has been used to identify Langerhans’ cell histiocytosis and precursor T lymphoblastic lymphoma/leukemia. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
CD1a [O10]
Description Cluster of Differentiation 1a (CD1a) is part of a family of major histocompatibility complex (MHC) antigen-like glycoproteins that associate with beta-2-microglobulin. CD1a binds self and non-self lipid and glycolipid antigens, presenting them to T-cell receptors on natural killer T-cells. CD1a antibody labels cortical thymocytes, Langerhans’ cells and dendritic cells. It has been used to identify Langerhans’ cell histiocytosis and precursor T lymphoblastic lymphoma/leukemia. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
CD2 [MD150R]
Description T-cell surface antigen CD2 (CD2) is a T-cell specific surface glycoprotein that is critically important for mediating adherence of T cells to antigen-presenting cells or target cells. It interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is involved in triggering T-cells, and the cytoplasmic domain is involved in signaling. CD2 is a pan T-cell marker. CD2 antibody labels T-cell, thymocytes and natural killer (NK) cells. CD2 is absent in a small subset of T cells. CD2 antibody is useful for identification of precursor and mature T-cell lymphomas. Aberrant loss of CD2 in T-cell lymphomas may help to distinguish them from reactive T-cell proliferations. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€416,00 Add to cart -
CD2 [MD150R]
Description T-cell surface antigen CD2 (CD2) is a T-cell specific surface glycoprotein that is critically important for mediating adherence of T cells to antigen-presenting cells or target cells. It interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is involved in triggering T-cells, and the cytoplasmic domain is involved in signaling. CD2 is a pan T-cell marker. CD2 antibody labels T-cell, thymocytes and natural killer (NK) cells. CD2 is absent in a small subset of T cells. CD2 antibody is useful for identification of precursor and mature T-cell lymphomas. Aberrant loss of CD2 in T-cell lymphomas may help to distinguish them from reactive T-cell proliferations. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€214,50 Add to cart -
CD20 (B Cell) [L26]
Description CD20 is a transmembrane phosphprotein which functions as a calcium-permeable cation channel involved in B cell activation, proliferation and differentiation. It is expressed on both normal and malignant B cells. The expression of CD20 is observed in all mature B lymphocytes but lost in terminal differentiated plasma cells. CD20 is one of the most important markers for B cell. It labels almost all mature B cell lymphoma, half of lymphoblastic lymphoma/leukemia and Reed-Sternberg cells in Hodgkin's disease. It has also been used to monitor down regulation of CD20 in patient treated with Rituximab for B cell lymphoma. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
CD20 (B Cell) [L26]
Description CD20 is a transmembrane phosphprotein which functions as a calcium-permeable cation channel involved in B cell activation, proliferation and differentiation. It is expressed on both normal and malignant B cells. The expression of CD20 is observed in all mature B lymphocytes but lost in terminal differentiated plasma cells. CD20 is one of the most important markers for B cell. It labels almost all mature B cell lymphoma, half of lymphoblastic lymphoma/leukemia and Reed-Sternberg cells in Hodgkin's disease. It has also been used to monitor down regulation of CD20 in patient treated with Rituximab for B cell lymphoma. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
CD205/LY75/gp200 [SPM487]
Description CD205, also named DEC-205, belongs to the macrophage mannose receptor family of C-type lectin endocytic receptors. CD205 is predominantly expressed by the thymic cortical epithelium and by dendritic cells (DC), but can also be detected at low levels in T and B lymphocytes and several other epithelial cell types. CD205 is a novel thymic epithelial marker that is important for the positive selection process of thymocytes. It is a sensitive and specific marker for thymoma, while the sensitivity to thymic carcinoma is lower than CD5 and CD117. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Horse
1 ml more info 14 days
€374,40 Add to cart
