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TCR γ/δ (TCR gamma/delta) [H41]
Description T-cell receptor (TCR), a heterodimer composed of either α and β or γ and δ chains, recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Most human T cells (95%) express the α/β or either CD4 or CD8 molecule (single positive, SP), while 2-5% express the γ/δ. However, a small number of T cells lack both CD4 and CD8 (double negative, DN). T helper cells express CD4 proteins and T cytotoxic cells display CD8. Increased percentages of α/β DN T cells have been identified in some autoimmune and immunodeficiency disorders. γ/δ T cells are primarily found within the epithelium. They show less TCR diversity and recognize antigens differently than α/β T cells. Subsets of γ/δ T cells have shown antitumor and immunoregulatory activity. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human 
1 ml more info 
14 days 
€374,40 Add to cart -
TCR γ/δ (TCR gamma/delta) [H41]
Description T-cell receptor (TCR), a heterodimer composed of either α and β or γ and δ chains, recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Most human T cells (95%) express the α/β or either CD4 or CD8 molecule (single positive, SP), while 2-5% express the γ/δ. However, a small number of T cells lack both CD4 and CD8 (double negative, DN). T helper cells express CD4 proteins and T cytotoxic cells display CD8. Increased percentages of α/β DN T cells have been identified in some autoimmune and immunodeficiency disorders. γ/δ T cells are primarily found within the epithelium. They show less TCR diversity and recognize antigens differently than α/β T cells. Subsets of γ/δ T cells have shown antitumor and immunoregulatory activity. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
TRPS1 [EPR16171]
Description Trichorhinophalangeal syndrome I (TRPS1), a transcriptional repressor, binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes. Defects in TRPS1 are the cause of tricho-rhino-phalangeal syndrome type 1. TRPS1 binds to the NuRD complex via CHD4 and can repress other key transcription factors such as p63 and estrogen receptor. It is expressed at higher levels in androgen-dependent prostate cancers, reducing the expression of PSA. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Monkey
1 ml more info 14 days
€507,00 Add to cart -
TRPS1 [EPR16171]
Description Trichorhinophalangeal syndrome I (TRPS1), a transcriptional repressor, binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes. Defects in TRPS1 are the cause of tricho-rhino-phalangeal syndrome type 1. TRPS1 binds to the NuRD complex via CHD4 and can repress other key transcription factors such as p63 and estrogen receptor. It is expressed at higher levels in androgen-dependent prostate cancers, reducing the expression of PSA. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Monkey
7 ml more info 14 days
€254,80 Add to cart -
Monoclonal antibody to monkey CD3 (clone FN-18)
Description The monoclonal antibody to monkey CD3 (clone FN-18) was first described in 1986. The FN-18 antibody can be used in immunohistochemical staining of frozen tissues, flow cytometric analysis and intracellular staining. Further, the antibody is able to stimulate rhesus macaque PBMC. The FN-18 antibody has been reported to cross react with rhesus macaque, cynomolgus monkey and baboon CD3. Other available formats: biotin labeled (cat. no. CT162) and FITC labeled (cat. no. CT163). (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application Flow cytometry (FC),Immunohistochemistry on frozen sections (IHC-Fs) Reactivity Rhesus Macaque,Cynomolgus Monkey,Baboon
0 mg more info 8 days
€440,00 Add to cart -
Monoclonal antibody to monkey CD3 biotin (clone FN-18)
Description The monoclonal antibody to monkey CD3 (clone FN-18) was first described in 1986. The FN-18 antibody can be used in flow cytometric analysis. The FN-18 antibody has been reported to cross react with rhesus macaque, cynomolgus macaque and baboon CD3. Other available formats: unconjugated (cat. no.CT161) and FITC labeled (cat. no.CT163). (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application Flow cytometry (FC) Reactivity Rhesus Macaque,Cynomolgus Monkey,Baboon Conjugate Biotin
50 ug more info 8 days
€385,00 Add to cart -
Monoclonal antibody to monkey CD3 FITC (clone FN-18)
Description The monoclonal antibody to monkey CD3 (clone FN-18) was first described in 1986. The FN-18 antibody can be used in flow cytometric analysis. The FN-18 antibody has been reported to cross react with rhesus macaque, cynomolgus macaque and baboon CD3. Other available formats: unconjugated (cat. no. CT161) and biotin labeled (cat. no. CT162). (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application Flow cytometry (FC) Reactivity Rhesus Macaque,Cynomolgus Monkey,Baboon Conjugate FITC
50 ug more info 8 days
€385,00 Add to cart -
Monoclonal antibody to human IFN-gamma (clone MD-1)
Description The monoclonal antibody to human IFN-γ (clone MD-1) was first described in 1985. It has shown to neutralize the antiviral activity of both natural and recombinant human IFN-γ and in a Western Blot the antibody reacts with the 20 kDa and 25 kDa polypeptides present in natural human IFN-γ. The MD-1 antibody has been descripted as useful in a sandwich ELISA and in ELISPOT assays. Further, the antibody has proven to cross react with chimpanzee and rhesus macaque IFN-γ and can be used for immunohistochemical staining of frozen tissues. The MD-1 antibody has been reported for use in intracellular flow cytometric analysis and in Luminex systems. Other available formats: biotin labeled (cat. no. CT218) and FITC labeled (cat. no. CT220). (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application ELISA,Enzyme-linked immunosorbent spot (ELISPOT),Flow cytometry (FC),Immunohistochemistry on frozen sections (IHC-Fs),Neutralization (Neut),Western Blot (WB) Reactivity Chimpanzee,Rhesus Macaque
0 0.5 mg more info 8 days
€305,00 Add to cart -
Monoclonal antibody to human IFN-gamma biotin (clone MD-1)
Description The monoclonal antibody to human IFN-γ was first described in 1985. It has shown to neutralize the antiviral activity of both natural and recombinant human IFN-γ and in a Western Blot the antibody reacts with the 20 kDa and 25 kDa polypeptides present in natural human IFN-γ. The MD-1 antibody has been descripted as useful in a sandwich ELISA. Further, the antibody has proven to cross react with rhesus macaque IFN-γ and can be used for immunohistochemical staining of frozen tissues. The MD-1 antibody has been reported for use in intracellular flow cytometric analysis. Other available formats: unconjugated (cat. no. CT215) and FITC labeled (cat. no. CT220). (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application ELISA,Flow cytometry (FC) Reactivity Chimpanzee,Rhesus Macaque Conjugate Biotin
0 0.5 mg more info 8 days
€385,00 Add to cart -
Monoclonal antibody to human IFN-gamma FITC (clone MD-1)
Description The monoclonal antibody to human IFN-γ (clone MD-1) was first described in 1985. It has shown to neutralize the antiviral activity of both natural and recombinant human IFN-γ and in a Western Blot the antibody reacts with the 20 kDa and 25 kDa polypeptides present in natural human IFN-γ. The antibody has proven to cross react with chimpanzee and rhesus macaque IFN-γ and can be used for immunohistochemical staining of frozen tissues. The MD-1 antibody has been reported for use in intracellular flow cytometric analysis. Other available formats: unconjugated (cat. no. CT215) and biotin labeled (cat. no. CT218). (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application Flow cytometry (FC),Immunohistochemistry on frozen sections (IHC-Fs) Reactivity Chimpanzee,Rhesus Macaque Conjugate FITC
50 ug more info 8 days
€385,00 Add to cart
