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MUC6 [CLH5]
Description Mucin 6 (Muc-6 Glycoprotein). Mucins are heavily glycosylated glycoproteins, which constitute the major components of mucus which cover the surface of epithelial tissues. Nine distinct epithelial mucin genes (Muc-1, 2, 3, 4, 5AC, 5B, 6,7 and 8) have been identified. Various immunohistochemical and in situ hybridization studies have shown that these mucins are differentially expressed in epithelia with cell-type specificity. Muc-5AC and Muc-6 glycoproteins are the first two mucins found in superficial epithelium and Muc-6 glycoprotein is found in the deep glands. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human 
1 ml more info 
14 days 
€361,40 Add to cart -
MUC6 [CLH5]
Description Mucin 6 (Muc-6 Glycoprotein). Mucins are heavily glycosylated glycoproteins, which constitute the major components of mucus which cover the surface of epithelial tissues. Nine distinct epithelial mucin genes (Muc-1, 2, 3, 4, 5AC, 5B, 6,7 and 8) have been identified. Various immunohistochemical and in situ hybridization studies have shown that these mucins are differentially expressed in epithelia with cell-type specificity. Muc-5AC and Muc-6 glycoproteins are the first two mucins found in superficial epithelium and Muc-6 glycoprotein is found in the deep glands. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
MUM1 [EP190]
Description MUM1 (multiple myeloma oncogene-1, also called IRF4), a member of the IRF family transcriptional factors, is induced by antigen receptor mediated stimuli and plays a crucial role in cell proliferation, differentiation and survival. In the hematolymphoid system, MUM1 is primarily expressed in B-cells and activated T-lymphoid cells. In B-cells it is expressed on a small subset of germinal center (GC) cells committed to plasmacytic or memory cell differentiation in the “light zone” and in plasma cells. MUM1 has been identified as a marker of non-germinal center-derived DLBCL, a subtype also associated with more aggressive clinical behavior and poor prognosis, but absent in mantle cell lymphoma (pre-GC B-cells) and in follicular lymphoma (GC B-cells). MUM1 may be a potential histo-genetic marker for B-cell lymphomas. Additionally, MUM1 is a useful marker for Reed-Sternberg (HRS) cells in Hodgkin’s lymphoma. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€494,00 Add to cart -
MUM1 [EP190]
Description MUM1 (multiple myeloma oncogene-1, also called IRF4), a member of the IRF family transcriptional factors, is induced by antigen receptor mediated stimuli and plays a crucial role in cell proliferation, differentiation and survival. In the hematolymphoid system, MUM1 is primarily expressed in B-cells and activated T-lymphoid cells. In B-cells it is expressed on a small subset of germinal center (GC) cells committed to plasmacytic or memory cell differentiation in the “light zone” and in plasma cells. MUM1 has been identified as a marker of non-germinal center-derived DLBCL, a subtype also associated with more aggressive clinical behavior and poor prognosis, but absent in mantle cell lymphoma (pre-GC B-cells) and in follicular lymphoma (GC B-cells). MUM1 may be a potential histo-genetic marker for B-cell lymphomas. Additionally, MUM1 is a useful marker for Reed-Sternberg (HRS) cells in Hodgkin’s lymphoma. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart -
Musashi1 (Msi1) [69-Q]
Description Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€361,40 Add to cart -
Musashi1 (Msi1) [69-Q]
Description Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Mouse, Rat
7 ml more info 14 days
€187,20 Add to cart -
Musashi2 (Msi2) Polyclonal
Description Musashi 2 (Msi2) protein, a regulator of mRNA translation, was consistently elevated in metastasis-competent cell lines. Msi2 is reported to be a potential oncoprotein in cases of leukemia and several solid tumors. The Msi2 RNA-binding protein has been demonstrated to have a role in acute myeloid leukemia and stem cell function. The Msi2 RNA-binding protein is a potent oncogene playing key roles in hematopoietic stem cell homeostasis and malignant hematopoiesis. Msi2 is expressed in the intestinal stem cell compartment, that its expression is elevated in colorectal adenocarcinomas, and that Msi2 loss-of-function abrogates colorectal cancer cell growth.Msi2 is highly expressed in human myeloid leukemia (AML) cell lines, and high expression of Msi2 mRNA is associated with decreased survival in AML, suggesting its use as a new prognostic marker. It has been demonstrated that Msi2 can induce bladder cancer cell migration and invasion by activating the JAK2/STAT3 pathway, and may be a valu Host Rabbit Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat 
1 ml more info 14 days
€401,70 Add to cart -
MVH/DDX4/VASA [2F9H5]
Description MVH or DDX4 or VASA is a 724 amino acid, ATP-dependent RNA helicase that belongs to the DEAD-box family. MVH is specifically expressed in germline cells throughout the life cycle and is undetectable in somatic tissues. In vertebrates, MVH is restricted to bisexually reproducing organisms. It is cytoplasmic and is present only in migratory primordial germ cells in the region of the gonadal ridge. On testicular sections, MVH expression is the highest in spermatogonia, reduced in spermatocytes, low in spermatids and absent in sperm. In the ovary, MVH expression is the highest in oogonia but persists throughout oogenesis. MVH has a glycine-rich N-terminus with multiple repeats of an RGG motif believed to function in RNA binding. Specifically, it regulates the translation of intricate mRNAs that are essential for differentiation. (Shipping Cost: €200.00) Host Mouse Application ELISA, Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB), Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
MxA/MX1/IFI78K [M143]
Description Interferon-induced GTP-binding protein Mx1 (UniProt P20591; also known as IFI-78K, Interferon-induced protein p78, Interferon-inducible protein p78, Interferon-regulated resistance GTP-binding protein MxA, Myxoma resistance protein 1, Myxovirus resistance 1) is encoded by the MX1 (also known as MX, IFI78) gene (Gene ID 4599) in human. The interferon-inducible myxovirus resistance (Mx) proteins belong to the family of large GTPases and are highly homologous with dynamins within their GTP-binding domain. Mx proteins differ from small GTPases and heterotrimeric G proteins in features such as their large size (70–100 kDa), a relatively low affinity for GTP, and a high intrinsic rate of GTP hydrolysis. Mx proteins contain a highly conserved tripartite GTP-binding motif within the N-terminal G domain, while their less conserved C-terminal half serves different functions such as homooligomerization and association with binding partners. Two distinct regions of human MxA, a central interactive Host Mouse Application Flow cytometry (FC), Immunohistochemistry (IHC), Western Blot (WB), Reactivity Human, Mouse, Rat, Guinea Pig
1 ml more info 14 days
€546,00 Add to cart -
Mycobacterium Bovis Polyclonal
Description Mycobacterium is a genus of actinobacteria, given its own family, the Mycobacteriaceae. It includes many pathogens known to cause serious diseases in mammals, including tuberculosis and leprosy. Mycobacteria can be classified into several major groups for purpose of diagnosis and treatment: M. tuberculosis complex which can cause tuberculosis: M. tuberculosis, M. bovis, M. africanum, and M. micoti. M. leprae which causes Hansen's disease or leprosy. Nontuberculous mycobacteria (NTM) are all the other mycobacteria which can cause pulmonary disease resembling tuberculosis, lymphadenitis, skin disease, or disseminated disease. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€546,00 Add to cart
