You are here
-
HPV 18 [HPV18/1297]
Description Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis has shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Type 18 of HPV 18 -
HSV I (HERPES SIMPLEX VIRUS TYPE I) [10A3]
Description The antibody reacts with HSV type 1 specific antigens and with antigens common for HSV types 1 and 2. The antibody reacts with all the major glycoproteins present in the viral envelope and at least one core protein as determined by crossed immunoelectrophoresis. It is well-suited for detection of HSV in human cellular material obtained from superficial lesions or biopsies and for the early identification of HSV in infected tissue cultures. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human -
HSV I (HERPES SIMPLEX VIRUS TYPE I) [10A3]
Description The antibody reacts with HSV type 1 specific antigens and with antigens common for HSV types 1 and 2. The antibody reacts with all the major glycoproteins present in the viral envelope and at least one core protein as determined by crossed immunoelectrophoresis. It is well-suited for detection of HSV in human cellular material obtained from superficial lesions or biopsies and for the early identification of HSV in infected tissue cultures. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human -
HSV II (Herpes Simplex Virus II) Polyclonal
Description Herpes simplex type 2 (HSV2) belongs to a family that includes HSV1, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus. HSV1 and HSV2 are extremely difficult to distinguish from each other. These viruses have a DNA genome, an icosahedral protein coat and are encased in a lipid membrane derived from the nuclear membrane of the last host. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell. This antibody reacts with HSV type II specific antigens and with antigens common to HSV type I and II virus. It reacts with all the major glycoproteins present in the viral envelop as well as with at least one core protein. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
HSV II (Herpes Simplex Virus II) Polyclonal
Description Herpes simplex type 2 (HSV2) belongs to a family that includes HSV1, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus. HSV1 and HSV2 are extremely difficult to distinguish from each other. These viruses have a DNA genome, an icosahedral protein coat and are encased in a lipid membrane derived from the nuclear membrane of the last host. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell. This antibody reacts with HSV type II specific antigens and with antigens common to HSV type I and II virus. It reacts with all the major glycoproteins present in the viral envelop as well as with at least one core protein. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
HTLV-1 Tax [1A3]
Description The Human T-lymphotropic virus Type I (HTLV-1) is a human RNA retrovirus that causes T-cell leukemia/lymphoma (ATL) in adults and may also be involved in certain demyelinating diseases, including tropical spastic paraparesis. The HTLV-1 genome is diploid, composed of two copies of a single-stranded RNA virus whose genome is copied into a double-stranded DNA form that integrates into the host cell genome, at which point the virus is referred to as a provirus. The glycoproteins encoded by the env gene of HTLV-1 are essential for interaction with an unidentified receptor on the surface of target cells and play a crucial role in the infection process. Encoded by HTLV-1 Tax is a phospho-oncoprotein that functions as a transcriptional activator. Tax has the ability to modulate the expression and function of many cellular genes and has been crucial to understanding the HTLV-1-mediated transformation of cells. In activating cellular gene expression, Tax impinges upon several cellular signal-tr Host Mouse Application ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity HTLV-1 -
HTLV-1 Tax [1A3]
Description The Human T-lymphotropic virus Type I (HTLV-1) is a human RNA retrovirus that causes T-cell leukemia/lymphoma (ATL) in adults and may also be involved in certain demyelinating diseases, including tropical spastic paraparesis. The HTLV-1 genome is diploid, composed of two copies of a single-stranded RNA virus whose genome is copied into a double-stranded DNA form that integrates into the host cell genome, at which point the virus is referred to as a provirus. The glycoproteins encoded by the env gene of HTLV-1 are essential for interaction with an unidentified receptor on the surface of target cells and play a crucial role in the infection process. Encoded by HTLV-1 Tax is a phospho-oncoprotein that functions as a transcriptional activator. Tax has the ability to modulate the expression and function of many cellular genes and has been crucial to understanding the HTLV-1-mediated transformation of cells. In activating cellular gene expression, Tax impinges upon several cellular signal-tr Host Mouse Application ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity HTLV-1 -
Human Chorionic Gonadotropin (HCG) alpha [HCGa/53]
Description Human Chorionic Gonadotropin (HCG) is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha- and Beta-subunits. The alpha-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP), and HCG but negative for EMA and AFP is probably a choriocarcinoma. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human -
Human Chorionic Gonadotropin (HCG) alpha [HCGa/53]
Description Human Chorionic Gonadotropin (HCG) is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha- and Beta-subunits. The alpha-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP), and HCG but negative for EMA and AFP is probably a choriocarcinoma. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human -
Human Chorionic Gonadotropin (HCG) beta [HCGb/54]
Description Human Chorionic Gonadotropin (HCG) is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha- and Beta-subunits. The alpha-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP), and HCG but negative for EMA and AFP is probably a choriocarcinoma. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human