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Cytokeratin 5/8 [C-50]
Description It reacts with keratin 5 (58kDa) and keratin 8 (52.5kDa). Simple epithelia express cytokeratin 8 in combination with 18. On the other hand, basal cells of stratified epithelia express cytokeratin 5 paired with 14. This antibody therefore, reacts with a wide range of epithelia and their carcinomas. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human,Pig (Porcine), Mouse, Rat, Hamster, Bovine, Dog (Canine), Sheep -
Cytokeratin 6 [LHK6]
Description The human type II Cytokeratin 6 (CK6; 56 kDa) is well known for its strong induction in stratified epithelia that feature an enhanced cell proliferation rate or abnormal differentiation during wound healing, in several diseases (e.g. psoriasis, actinic keratosis) and in cancer. CK6 is expressed on stratified epithelia including oral mucosa, esophagus, basal layer of epidermis, the outer root sheath of hair follicles, and in glandular epithelia. CK6 is a marker of hyperproliferative and activated keratinocytes found in psoriasis. CK6 paired with CK5 is useful to differentiate mesothelioma (positive) from lung carcinoma (negative) or metastatic carcinoma (negative) in the pleura. CK5/6 has also been used to distinguish usual ductal hyperplasia of the breast (strong staining) from solid papillary DCIS (negative). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse -
Cytokeratin 6 [LHK6]
Description The human type II Cytokeratin 6 (CK6; 56 kDa) is well known for its strong induction in stratified epithelia that feature an enhanced cell proliferation rate or abnormal differentiation during wound healing, in several diseases (e.g. psoriasis, actinic keratosis) and in cancer. CK6 is expressed on stratified epithelia including oral mucosa, esophagus, basal layer of epidermis, the outer root sheath of hair follicles, and in glandular epithelia. CK6 is a marker of hyperproliferative and activated keratinocytes found in psoriasis. CK6 paired with CK5 is useful to differentiate mesothelioma (positive) from lung carcinoma (negative) or metastatic carcinoma (negative) in the pleura. CK5/6 has also been used to distinguish usual ductal hyperplasia of the breast (strong staining) from solid papillary DCIS (negative). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse -
Cytokeratin 7 [OV-TL12/30]
Description Cytokeratin 7 (CK7) is a cytoplasmic intermediate filament protein expressed on most ductal and glandular epithelium including lung, breast, bladder and female genital tract, but not in most gastrointerstinal epithelium, prostate, hepatocyte and squamous epithelium. CK7 expression is absent in colon cancer, prostate cancer and squamous carcinomas. The restricted expression of CK7 in some epithelium makes it useful to identify the organ origin of adenocarcinomas when combined with staining of Cytokeratin 20 and other cell specific markers. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human -
Cytokeratin 7 [OV-TL12/30]
Description Cytokeratin 7 (CK7) is a cytoplasmic intermediate filament protein expressed on most ductal and glandular epithelium including lung, breast, bladder and female genital tract, but not in most gastrointerstinal epithelium, prostate, hepatocyte and squamous epithelium. CK7 expression is absent in colon cancer, prostate cancer and squamous carcinomas. The restricted expression of CK7 in some epithelium makes it useful to identify the organ origin of adenocarcinomas when combined with staining of Cytokeratin 20 and other cell specific markers. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human -
Cytokeratin 8 [35BH11]
Description Cytokeratin 8 (CK8) is an intermediate filament protein produced early in embryogenesis. It is the only type-II CK occurring in many simple epithelial in respiratory, gastrointestinal, male and female reproductive tract and thyroid. CK8 is often co-expressed with Cytokeratin 18. CK8/18 is the major keratin pair in simple-type epithelia, as found in the liver, pancreas, and intestine. CK8 is used to detect adenocarcinomas with simple epithelium origin. The difference in staining pattern is useful to distinguish duct (peripheral staining) from lobular (perinuclear staining) breast carcinoma. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human -
Cytokeratin 8 [35BH11]
Description Cytokeratin 8 (CK8) is an intermediate filament protein produced early in embryogenesis. It is the only type-II CK occurring in many simple epithelial in respiratory, gastrointestinal, male and female reproductive tract and thyroid. CK8 is often co-expressed with Cytokeratin 18. CK8/18 is the major keratin pair in simple-type epithelia, as found in the liver, pancreas, and intestine. CK8 is used to detect adenocarcinomas with simple epithelium origin. The difference in staining pattern is useful to distinguish duct (peripheral staining) from lobular (perinuclear staining) breast carcinoma. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human -
Cytokeratin 8/18 [K8.8&DC10]
Description Cytokeratin 8 (CK8) is an intermediate filament protein produced early in embryogenesis. It is the only type-II CK occurring in many simple epithelial cells in respiratory, gastrointestinal, male and female reproductive tracts, and thyroid. CK8 is often co-expressed withCytokeratin 18. CK8/18 is the major keratin pair in simple-type epithelia, as found in the liver, pancreas, and intestine. The CK8 antibody is used to detect adenocarcinomas of simple epithelium origin. The difference in staining pattern is useful to distinguish ductal (peripheral staining) from lobular (perinuclear staining) breast carcinoma. Cytokeratin 18 (CK18) is an intermediate filament phosphoglycoprotein that is expressed in simple and glandular and transitional epithelial cells, but not in stratified epithelial cells. CK18 is often co-expressed with CK8. CK8/18 is the major keratin pair in simple-type epithelia. Adenocarcinomas originated from simple and glandular epithelium showed CK18 positive staining. In sq Host Mouse Application Immunohistochemistry (IHC) Reactivity Human -
Cytokeratin 8/18 [K8.8&DC10]
Description Cytokeratin 8 (CK8) is an intermediate filament protein produced early in embryogenesis. It is the only type-II CK occurring in many simple epithelial cells in respiratory, gastrointestinal, male and female reproductive tracts, and thyroid. CK8 is often co-expressed withCytokeratin 18. CK8/18 is the major keratin pair in simple-type epithelia, as found in the liver, pancreas, and intestine. The CK8 antibody is used to detect adenocarcinomas of simple epithelium origin. The difference in staining pattern is useful to distinguish ductal (peripheral staining) from lobular (perinuclear staining) breast carcinoma. Cytokeratin 18 (CK18) is an intermediate filament phosphoglycoprotein that is expressed in simple and glandular and transitional epithelial cells, but not in stratified epithelial cells. CK18 is often co-expressed with CK8. CK8/18 is the major keratin pair in simple-type epithelia. Adenocarcinomas originated from simple and glandular epithelium showed CK18 positive staining. In sq Host Mouse Application Immunohistochemistry (IHC) Reactivity Human -
Cytokeratin Acid [AE1]
Description Each epithelium contains at least one acidic and one basic keratin. Anti-Cytokeratin clone AE1 labels most acidic keratins and stains most epithelia and their neoplasms. The antibody is suited to distinguish poorly differentiated carcinomas from non-epithelial neoplasms. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Monkey, Bovine, Dog (Canine), Rabbit, Mouse, Rat, Chicken, Turtle