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Cytokeratin 7 [OV-TL12/30]

Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: OV-TL12/30
Host: Mouse
Isotype: IgG
Application: Immunohistochemistry (IHC)
Application notes: Prediluted
Conjugation Type: Unconjugated
Reactivity: Human
General notes: Localization: cytoplasm.
Buffer: citrate pH6.0
UNSPSC code: 12352203

Cytokeratin 7 (CK7) is a cytoplasmic intermediate filament protein expressed on most ductal and glandular epithelium including lung, breast, bladder and female genital tract, but not in most gastrointerstinal epithelium, prostate, hepatocyte and squamous epithelium. CK7 expression is absent in colon cancer, prostate cancer and squamous carcinomas. The restricted expression of CK7 in some epithelium makes it useful to identify the organ origin of adenocarcinomas when combined with staining of Cytokeratin 20 and other cell specific markers. (Shipping Cost: €200.00)

Cytokeratin 7 [OV-TL12/30]

Cytokeratin 7 (CK7) is a cytoplasmic intermediate filament protein expressed on most ductal and glandular epithelium including lung, breast, bladder and female genital tract, but not in most gastrointerstinal epithelium, prostate, hepatocyte and squamous epithelium. CK7 expression is absent in colon cancer, prostate cancer and squamous carcinomas. The restricted expression of CK7 in some epithelium makes it useful to identify the organ origin of adenocarcinomas when combined with staining of Cytokeratin 20 and other cell specific markers.