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VEGFC (Flt4L) Polyclonal
Description Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. (Shipping Cost: €200.00) Host Rabbit Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat 
7 ml more info 
14 days 
€201,50 Add to cart -
Vimentin [V9]
Description Anti-vimentin is of limited value as a diagnostic tool; however, when used in combination with other antibodies (in panels) it is useful for the subclassification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. This antibody recognizes a 57 kD intermediate filament. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human 
1 ml more info 14 days
€361,40 Add to cart -
Vimentin [V9]
Description Anti-vimentin is of limited value as a diagnostic tool; however, when used in combination with other antibodies (in panels) it is useful for the subclassification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. This antibody recognizes a 57 kD intermediate filament. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
VIP Polyclonal
Description Vasoactive intestinal peptide (VIP) is a 28 amino acid neuropeptide that has been isolated from various organs like intestine the brain upper respiratory and nasal mucosa, salivary glands, and the male and female genital tracts. It is also identifiable in human eosinophils, polymorphonuclear and mononuclear leucocytes. VIP is also known as a potent stimulant of mucous secretion, vasodilatation, and smooth muscle relaxation in bronchus and many other organs. According to various studies, VIP also has effects on the immune regulation. In the murine immune system, VIP inhibited the proliferative responses of lymphocytes to the T cell mitogens. VIP is also known to have altered preferentially IgA synthesis by lymphocytes from gastrointestinal tissues and spleen. In the human immune system, VIP is known to have inhibited the proliferative response of T lymphocytes to mercuric chloride, and inhibited natural killer (NK) cell function. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
VIP Polyclonal
Description Vasoactive intestinal peptide (VIP) is a 28 amino acid neuropeptide that has been isolated from various organs like intestine the brain upper respiratory and nasal mucosa, salivary glands, and the male and female genital tracts. It is also identifiable in human eosinophils, polymorphonuclear and mononuclear leucocytes. VIP is also known as a potent stimulant of mucous secretion, vasodilatation, and smooth muscle relaxation in bronchus and many other organs. According to various studies, VIP also has effects on the immune regulation. In the murine immune system, VIP inhibited the proliferative responses of lymphocytes to the T cell mitogens. VIP is also known to have altered preferentially IgA synthesis by lymphocytes from gastrointestinal tissues and spleen. In the human immune system, VIP is known to have inhibited the proliferative response of T lymphocytes to mercuric chloride, and inhibited natural killer (NK) cell function. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€163,80 Add to cart -
Wilms' Tumor (WT1) [EP122]
Description WT1 is a suppressor gene located on chromosome 11p13. Wilms’ Tumor protein (WT1) has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€494,00 Add to cart -
Wilms' Tumor (WT1) [EP122]
Description WT1 is a suppressor gene located on chromosome 11p13. Wilms’ Tumor protein (WT1) has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart -
ZAP70 [EP52]
Description ZAP-70 is a 70 kD protein tyrosine kinase found in T-cells and natural killer cells. Control of this protein translation is via the IgVH gene. ZAP-70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well. Anti-ZAP-70 expression is an excellent surrogate marker for the distinction between the Ig-mutated (anti-ZAP-70 negative) and Ig-unmutated (anti-ZAP-70 positive) CLL subtypes and can identify patient groups with divergent clinical courses. The anti-ZAP-70 positive Ig-unmutated CLL cases have been shown to have a poorer prognosis. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€494,00 Add to cart -
ZAP70 [EP52]
Description ZAP-70 is a 70 kD protein tyrosine kinase found in T-cells and natural killer cells. Control of this protein translation is via the IgVH gene. ZAP-70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well. Anti-ZAP-70 expression is an excellent surrogate marker for the distinction between the Ig-mutated (anti-ZAP-70 negative) and Ig-unmutated (anti-ZAP-70 positive) CLL subtypes and can identify patient groups with divergent clinical courses. The anti-ZAP-70 positive Ig-unmutated CLL cases have been shown to have a poorer prognosis. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart -
CD3 [MD202R]
Description CD3 is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell and T helper cells. It is composed of four distinct chains CD3γ, CD3δ, and two CD3ε chains in mammals. These chains associate with the T-cell receptor (TCR) and the CD3-zeta (ζ-chain) to generate activation signal in T lymphocytes. The TCR, CD3-zeta, and the other CD3 molecules together constitute the TCR complex. CD3 is initially expressed in the cytoplasm of pro-thymocytes, the stem cells from which T-cells arise in the thymus. The pro-thymocytes differentiate into common thymocytes, and then into medullary thymocytes, and it is at this latter stage that CD3 antigen begins to migrate to the cell membrane. The antigen is highly specific marker for T cells, remains present in almost all T-cell lymphomas and leukaemias, and can therefore be used to distinguish them from superficially similar B-cell and myeloid neoplasms. This monoclonal antibody recognizes the epsilon-chain of CD3. C Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€401,70 Add to cart
