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Growth Hormone (HGH) [GH/1450]
Description Growth hormone (GH or hGH), also known as somatotropin or somatropin, is a peptide hormone that is produced and secreted by somatotrophs of the anterior pituitary gland. GH exerts a wide variety of biological actions in many different tissues and cell types. The actions of GH at the cellular level can be divided into three categories: those affecting mitogenesis, differentiation, and metabolism. The GH antibody specifically labels somatotrophs in pituitary in normal tissues. It is useful in classification of pituitary tumor. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human 
7 ml more info 
14 days 
€187,20 Add to cart -
Hairy Cell Leukemia [DBA.44]
Description Hairy cell leukemia (HCL) is a rare type of chronic lymphoid leukemia. The disease is characterized by abnormal white blood cells bearing hair-like projections from the cytoplasm. These cancerous cells are larger than normal and positive for CD19, CD20, CD22, CD11c, CD25, CD103 and FMC7. HCL commonly causes infection, anemia and/or easy bleeding in patients. Some of the leukemic cells may gather in the spleen and cause it to swell, leading to massive splenomegaly. Patients with a high tumor burden may also have significantly reduced levels of cholesterol. There are two variants of hairy cell leukemia: hairy cell leukemia-variant, which is usually diagnosed in older men; and a Japanese variant. HCL markers are important research tools as they allow for the functional and behavioral analysis of this type of leukemia. DBA.44, a B subset antibody, reacts with very few normal cells. 50-97% of HCL cases are positive; about 35% of low grade B-cell lymphomas are positive; and about 30-80% of s Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€401,70 Add to cart -
Hairy Cell Leukemia [DBA.44]
Description Hairy cell leukemia (HCL) is a rare type of chronic lymphoid leukemia. The disease is characterized by abnormal white blood cells bearing hair-like projections from the cytoplasm. These cancerous cells are larger than normal and positive for CD19, CD20, CD22, CD11c, CD25, CD103 and FMC7. HCL commonly causes infection, anemia and/or easy bleeding in patients. Some of the leukemic cells may gather in the spleen and cause it to swell, leading to massive splenomegaly. Patients with a high tumor burden may also have significantly reduced levels of cholesterol. There are two variants of hairy cell leukemia: hairy cell leukemia-variant, which is usually diagnosed in older men; and a Japanese variant. HCL markers are important research tools as they allow for the functional and behavioral analysis of this type of leukemia. DBA.44, a B subset antibody, reacts with very few normal cells. 50-97% of HCL cases are positive; about 35% of low grade B-cell lymphomas are positive; and about 30-80% of s Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart -
Hamartin/TSC1 [C-8]
Description Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each ther forming a cystoplasmic complex. Hamartin interacts with the ezrinradixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
Hamartin/TSC1 [C-8]
Description Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each ther forming a cystoplasmic complex. Hamartin interacts with the ezrinradixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
HBsAg [A10F1]
Description Hepatitis B virus causes type B hepatitis and it belongs to hepadnavirus family. It is spherical in shape with a diameter of 42 nm. It contains a 27 nm partially double stranded DNA core enclosed within a lipoprotein coat. The antigenic activity of the nucleocapsid core is designated as hepatitis B core antigen. The antigens in the outer surface are called as hepatitis B virus surface antigens. Core antigens are localized within the nuclei whereas the surface antigens are present in the cytoplasm of the infected cells. Antibodies to surface antigens appear in circulation at an early stage of infection whereas the antibodies to the core antigens are detected after several weeks. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity HBV
1 ml more info 14 days
€361,40 Add to cart -
HCV Core NS4 [5D4/10E7]
Description The Hep C (Hepatitis C) is a small, enveloped, single-stranded, positive sense RNA virus belonging to the family Flaviviridae. Transmission of the virus occurs when blood from an infected individual enters the body of an uninfected individual. Hep C primarily replicates within hepatocytes in the liver, and circulating Hep C particles bind to receptors on the surface and enter these cells. Hep C replicates quickly, producing approximately one trillion particles each day in infected individuals. Hep C RNA polymerase has no proofreading function, so the virus has an exceptionally high mutation rate which may help it elude the host's immune system. Hep C infection results in chronic infections, liver cirrhosis, and hepatocellular carcinoma in most people. Hep C NS3 (nonstructural protein 3) has both protease and helicase activities and is essential for Hep C replication and proliferation. Hep C NS4 (nonstructural protein 4) augments the proteolytic activity of Hep C NS3 through protein-pro Host Mouse Application Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
HCV Core NS4 [5D4/10E7]
Description The Hep C (Hepatitis C) is a small, enveloped, single-stranded, positive sense RNA virus belonging to the family Flaviviridae. Transmission of the virus occurs when blood from an infected individual enters the body of an uninfected individual. Hep C primarily replicates within hepatocytes in the liver, and circulating Hep C particles bind to receptors on the surface and enter these cells. Hep C replicates quickly, producing approximately one trillion particles each day in infected individuals. Hep C RNA polymerase has no proofreading function, so the virus has an exceptionally high mutation rate which may help it elude the host's immune system. Hep C infection results in chronic infections, liver cirrhosis, and hepatocellular carcinoma in most people. Hep C NS3 (nonstructural protein 3) has both protease and helicase activities and is essential for Hep C replication and proliferation. Hep C NS4 (nonstructural protein 4) augments the proteolytic activity of Hep C NS3 through protein-pro Host Mouse Application Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
HDAC1/HD1 [10E2]
Description Acetylation of the histone tail causes chromatin to adopt an “open” conformation, allowing increased accessibility of transcription factors to DNA. The identification of histone acetyltransferases (HATs) and their large multiprotein complexes has yielded important insights into how these enzymes regulate transcription. HAT complexes interact with sequence-specific activator proteins to target specific genes. In addition to histones, HATs can acetylate non-histone proteins, suggesting multiple roles for these enzymes. In contrast, histone deacetylation promotes a “closed” chromatin conformation and typically leads to repression of gene activity. Mammalian histone deacetylases can be divided into three classes on the basis of their similarity to various yeast deacetylases. Class I (HDACs 1, 2, 3 and 8) proteins are related to the yeast Rpd3-like proteins, those in class II (HDACs 4, 5, 6, 7, 9 and 10) are related to yeast Hda1-like proteins and class III proteins are related to the yeast Host Mouse Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€361,40 Add to cart -
Heat Shock Protein (HSP27) [G3.1]
Description HSP 27 also known as 24K estrogen-regulated protein or HSP 28 is a small heat shock protein that has been shown to correlate with the expression of estrogen-receptor. Immunohistochemical studies of HSP 27 has shown that it is localized mainly in the female reproductive tract and in ER and PR positive breast tumor cell lines. Increased levels of HSP 27 have been shown to correlate with the presence of ER and PR in human breast tumor biopsy samples. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Chimpanzee, Monkey, Sheep, Rat, Mouse, Chicken
1 ml more info 14 days
€361,40 Add to cart
