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Purified anti-human CD180 (RP105)
Description Purified anti-human CD180 (RP105) MHR73-11 100 µg (Shipping Cost: €40.00) Host Mouse Reactivity Human Concentration 0.5 mg/ml Specificity CD180 (RP105) -
PE anti-human CD180 (RP105)
Description PE anti-human CD180 (RP105) MHR73-11 100 tests (Shipping Cost: €40.00) Host Mouse Reactivity Human Concentration Lot-specific Conjugate Phycoerythrin (PE) Specificity CD180 (RP105) -
PE/Cy7 anti-human CD180 (RP105)
Host Mouse Reactivity Human Conjugate PE/Cy7™ tandem -
PE/Cy7 anti-human CD180 (RP105)
Host Mouse Reactivity Human Conjugate PE/Cy7™ tandem -
APC anti-human CD180 (RP105)
Host Mouse Reactivity Human Conjugate Allophycocyanin (APC) -
APC anti-human CD180 (RP105)
Host Mouse Reactivity Human Conjugate Allophycocyanin (APC) -
CD180/RP105 [MHR73-11]
Description CD180 or RP105, BGP95, LY64) is a type I membrane glycoprotein of Toll-like receptor (TLR) family. Its cytoplasmic tail is short and unlike the TLRs, it lacks the TIR domain. CD180 expression depends on the coexpression of its helper molecule, MD-1 , and mirrors that of TLR4 on antigen-presenting cells. CD180 regulates recognition of LPS and signaling in B cells, via interacting directly with the TLR4 signaling complex, inhibiting its ability to bind microbial ligands. Ligation of CD180 by monoclonal antibodies leads to B cell activation, upregulation of CD80/CD86, and increase in cell size. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Baboon, Cynomolgus, African Green, Rhesus