| Quantity | Title | Price |
|---|---|---|
| 1 × | APC/Fire™ 750 anti-mouse CD105 | 0 |
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TAG-72/CA72.4 [B72.3]
Description Tumor-Associated Glycoprotein 72 (TAG-72) is an oncofetal mucin antigen expressed by normal secretory endometrium and most human adenocarcinomas, including colorectal, gastric, pancreatic, mammary, and ovarian. Antibody B72.3 recognizes a carbohydrate epitope identified as sialylated Tn antigen. This antigen is expressed by invasive ductal breast carcinomas, colon, pancreatic, gastric, esophageal, lung, ovarian and endometrial adenocarcinomas. It is not expressed by leukemias, lymphomas, sarcomas, mesotheliomas, melanomas, or benign tumors. This antigen is also expressed on normal secretory endometrium, but not on other normal tissues. TAG-72 expression in fetal tissue is only observed in tissues of the gastrointestinal tract, including the colon, esophagus and stomach. No reactivity is seen with tissue from other organ systems, including the lymphoreticular, cardiovascular, hepatic, pulmonary, neural, muscular, skin, endocrine and genitourinary tissues. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Bovine, Dog (Canine), Hamster, Rat 
7 ml more info 
14 days 
€187,20 Add to cart -
Tartarate Resistant Acid Phosphatase (TRAcP/TRAP5) [ACP5/1070]
Description Tartrate resistant acid phosphatase (TRAcP) is a basic, iron-binding protein with high activity towards phosphoproteins, ATP and 4 nitrophenyl phosphate. Expression of TRAcP is reported to be increased in the spleen and monocytes of individuals with Gaucher’s disease, splenocytes and circulating white cells of individuals with hairy cell leukemia, spleens of individuals with Hodgkin disease, and the sera of individuals undergoing active bone turnover. Elevated levels are also reported to be associated with various B-cell and T-cell leukemias and lymphomas, placental decidual cells, syncytiotrophoblasts, and some macrophages distributed throughout maternal and embryonic tissues. The histochemical identification of hairy cell leukemia via tartrate-resistant acid phosphatase assay has been a standard for over two decades. Anti-TRAcP labels the cells of hairy cell leukemia (HCL) with a high degree of sensitivity and specificity. Worthy also of mention in this regard are anti-annexin A1 and Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse,Rat
1 ml more info 14 days
€361,40 Add to cart -
Tartarate Resistant Acid Phosphatase (TRAcP/TRAP5) [ACP5/1070]
Description Tartrate resistant acid phosphatase (TRAcP) is a basic, iron-binding protein with high activity towards phosphoproteins, ATP and 4 nitrophenyl phosphate. Expression of TRAcP is reported to be increased in the spleen and monocytes of individuals with Gaucher’s disease, splenocytes and circulating white cells of individuals with hairy cell leukemia, spleens of individuals with Hodgkin disease, and the sera of individuals undergoing active bone turnover. Elevated levels are also reported to be associated with various B-cell and T-cell leukemias and lymphomas, placental decidual cells, syncytiotrophoblasts, and some macrophages distributed throughout maternal and embryonic tissues. The histochemical identification of hairy cell leukemia via tartrate-resistant acid phosphatase assay has been a standard for over two decades. Anti-TRAcP labels the cells of hairy cell leukemia (HCL) with a high degree of sensitivity and specificity. Worthy also of mention in this regard are anti-annexin A1 and Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse,Rat
7 ml more info 14 days
€187,20 Add to cart -
T-bet/TBX21 [MD40R]
Description T-box transcription factor TBX21, also known as T-bet, is a member of the T-box family of transcription factors. It has been confirmed that TBX21 is the key lineage-defining transcription factor that directs the development Th1 cells and is directly responsible for the transactivation of the interferon-γ (IFN-γ) gene. TBX21 is expressed in CD4+ T lymphocytes in normal tissues. In lymphoid malignancies, TBX21 has been found in a subset of T-cell lymphomas with Th1 T-cell differentiation, a subset of B-cell or T cells, non-Hodgkin's lymphomas, majority of Hodgkin's lymphomas and precursor B-cell lymphoblastic leukemia/lymphoblastic lymphomas. However, TBX21 is not expressed in diffuse large B-cell lymphoma and most cases of anaplastic large cell lymphoma. TBX21 is a useful new marker for Hodgkin's lymphoma. TBX21 is also helpful in identification of hairy cell leukemia (HCL). Ventana/Cell Marque have. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€401,70 Add to cart -
T-bet/TBX21 [MD40R]
Description T-box transcription factor TBX21, also known as T-bet, is a member of the T-box family of transcription factors. It has been confirmed that TBX21 is the key lineage-defining transcription factor that directs the development Th1 cells and is directly responsible for the transactivation of the interferon-γ (IFN-γ) gene. TBX21 is expressed in CD4+ T lymphocytes in normal tissues. In lymphoid malignancies, TBX21 has been found in a subset of T-cell lymphomas with Th1 T-cell differentiation, a subset of B-cell or T cells, non-Hodgkin's lymphomas, majority of Hodgkin's lymphomas and precursor B-cell lymphoblastic leukemia/lymphoblastic lymphomas. However, TBX21 is not expressed in diffuse large B-cell lymphoma and most cases of anaplastic large cell lymphoma. TBX21 is a useful new marker for Hodgkin's lymphoma. TBX21 is also helpful in identification of hairy cell leukemia (HCL). Ventana/Cell Marque have. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart -
Tenascin [T2H5]
Description Tenascin is a high molecular weight, multifunctional, hexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neovasculature and stroma of undifferentiated tumors. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
Tenascin [T2H5]
Description Tenascin is a high molecular weight, multifunctional, hexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neovasculature and stroma of undifferentiated tumors. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
Thrombomodulin (CD141) [D3]
Description Thrombomodulin (TM), also known as CD141, is an endothelial-specific type I membrane receptor that binds thrombin, resulting in the activation of protein C. This causes the degradation of clotting factors Va and VIIIa and reduces the amount of thrombin generated. Defect in Thrombomodulin is a cause of thromboembolic disease, also known as inherited thrombophilia. Thrombomodulin was initially identified in endothelial cells. Its expression was also found in extra-vascular sites, such as in syncytiotrophoblasts in the placenta, epithelial tissues in the gingiva, in skin and in the synovial lining cells. In tumors, Thrombomodulin is expressed in vascular tumors and squamous cell carcinoma in a variety of tissues, including oral mucosa, esophagus and skin. Thrombomodulin is a marker for angiosarcoma. Additionally, anti-Thrombomodulin is useful in differentiating mesothelioma (positive) from lung adenocarcinoma (negative). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
Thrombomodulin (CD141) [D3]
Description Thrombomodulin (TM), also known as CD141, is an endothelial-specific type I membrane receptor that binds thrombin, resulting in the activation of protein C. This causes the degradation of clotting factors Va and VIIIa and reduces the amount of thrombin generated. Defect in Thrombomodulin is a cause of thromboembolic disease, also known as inherited thrombophilia. Thrombomodulin was initially identified in endothelial cells. Its expression was also found in extra-vascular sites, such as in syncytiotrophoblasts in the placenta, epithelial tissues in the gingiva, in skin and in the synovial lining cells. In tumors, Thrombomodulin is expressed in vascular tumors and squamous cell carcinoma in a variety of tissues, including oral mucosa, esophagus and skin. Thrombomodulin is a marker for angiosarcoma. Additionally, anti-Thrombomodulin is useful in differentiating mesothelioma (positive) from lung adenocarcinoma (negative). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
Thymidylate Synthase (TS) [TS106]
Description TS (EC:2.1.1.45), a cytosolic enzyme, is a dimmer of two identical monomers of about 36kDa. The enzyme provides the sole intracellular de novo source of thymidylate and plays a crucial role in DNA replication and repair. TS catalyzes the methylation of deoxyuridine monophosphate (dump) and its conversion to deoxythymidine monophosphate (dTMP). Therefore, TS is primarily active in proliferating and metabolic active cells. TS is a central target of the widely used antineoplastic agent 5-Fluorouracil (5-FU) and thus also of the Xeloda, which is enzymatically activated to 5-FU. TS is inactivated by a covalent complex formation with 5-FdUMP and methylenetetrahydrofolate. Literature indicates that expression of TS is associated with response to 5-fluorouracil (5-FU) in human breast, colorectal, gastric, head, and neck carcinomas with low TS expression predicting better response to 5-FU and survival. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart
