Ultra-Sensitive ASXL1 Exon 12 mutation detection kit (Shipping Cost: €200.00)

Ultra-Sensitive ASXL1 Exon 12 mutation detection kit

ASXL1 gene, somatic mutations in the additional sex comb-like 1 (ASXL1), are involved in the regulation or recruitment of the Polycomb-group repressor complex (PRC) and trithorax-group (trxG) activator complex. Recently, ASXL1 gene profiling has been studied in various types of diseases, which is also considered as a novel marker which may be a risk factor related with the prevalence and prognostic of myelodysplastic syndromes. In addition, more and more studies indicate that ASXL1 mutations may be associated with a poor outcome.|Medaysis Ultra-Sensitive cfDNA ASXL1 Mutation Detection Kit is a highly specific and sensitive PCR technique that is able to detect common somatic mutations in the ASXL1 gene. Used with Sanger sequencing, it can detect less than 1% (as little as 20 ng to 100 ng of) mutant genes mixed with the wild type. It is designed to amplify ASXL1 gene in circulating cell-free DNA (cfDNA) from liquid biopsies or blood samples.|The feature of Medaysis mutation detection kit:1. Detect known and unknown mutation in target Exons2. Highly specific and sensitive mutation enrich technology3. Open system and easy to be done4. Minimal sample size - 5. No microdissection required

Ultra-Sensitive ASXL1 Exon 12 mutation detection kit