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Granzyme B [GZMB/3014]
Description Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of T/NK-cell lymphomas in conjunction with CD56 (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human 
7 ml more info 
14 days 
€187,20 Add to cart -
Growth Hormone (HGH) [GH/1450]
Description Growth hormone (GH or hGH), also known as somatotropin or somatropin, is a peptide hormone that is produced and secreted by somatotrophs of the anterior pituitary gland. GH exerts a wide variety of biological actions in many different tissues and cell types. The actions of GH at the cellular level can be divided into three categories: those affecting mitogenesis, differentiation, and metabolism. The GH antibody specifically labels somatotrophs in pituitary in normal tissues. It is useful in classification of pituitary tumor. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
Growth Hormone (HGH) [GH/1450]
Description Growth hormone (GH or hGH), also known as somatotropin or somatropin, is a peptide hormone that is produced and secreted by somatotrophs of the anterior pituitary gland. GH exerts a wide variety of biological actions in many different tissues and cell types. The actions of GH at the cellular level can be divided into three categories: those affecting mitogenesis, differentiation, and metabolism. The GH antibody specifically labels somatotrophs in pituitary in normal tissues. It is useful in classification of pituitary tumor. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
Hairy Cell Leukemia [DBA.44]
Description Hairy cell leukemia (HCL) is a rare type of chronic lymphoid leukemia. The disease is characterized by abnormal white blood cells bearing hair-like projections from the cytoplasm. These cancerous cells are larger than normal and positive for CD19, CD20, CD22, CD11c, CD25, CD103 and FMC7. HCL commonly causes infection, anemia and/or easy bleeding in patients. Some of the leukemic cells may gather in the spleen and cause it to swell, leading to massive splenomegaly. Patients with a high tumor burden may also have significantly reduced levels of cholesterol. There are two variants of hairy cell leukemia: hairy cell leukemia-variant, which is usually diagnosed in older men; and a Japanese variant. HCL markers are important research tools as they allow for the functional and behavioral analysis of this type of leukemia. DBA.44, a B subset antibody, reacts with very few normal cells. 50-97% of HCL cases are positive; about 35% of low grade B-cell lymphomas are positive; and about 30-80% of s Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€401,70 Add to cart -
Hairy Cell Leukemia [DBA.44]
Description Hairy cell leukemia (HCL) is a rare type of chronic lymphoid leukemia. The disease is characterized by abnormal white blood cells bearing hair-like projections from the cytoplasm. These cancerous cells are larger than normal and positive for CD19, CD20, CD22, CD11c, CD25, CD103 and FMC7. HCL commonly causes infection, anemia and/or easy bleeding in patients. Some of the leukemic cells may gather in the spleen and cause it to swell, leading to massive splenomegaly. Patients with a high tumor burden may also have significantly reduced levels of cholesterol. There are two variants of hairy cell leukemia: hairy cell leukemia-variant, which is usually diagnosed in older men; and a Japanese variant. HCL markers are important research tools as they allow for the functional and behavioral analysis of this type of leukemia. DBA.44, a B subset antibody, reacts with very few normal cells. 50-97% of HCL cases are positive; about 35% of low grade B-cell lymphomas are positive; and about 30-80% of s Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart -
Hamartin/TSC1 [C-8]
Description Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each ther forming a cystoplasmic complex. Hamartin interacts with the ezrinradixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
Hamartin/TSC1 [C-8]
Description Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each ther forming a cystoplasmic complex. Hamartin interacts with the ezrinradixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
HBcAg Polyclonal
Description Hepatitis B virus is spherical in shape with a diameter of 42 nm. It contains a 27 nm partially double stranded DNA core enclosed within a lipoprotein coat. The antigenic activity of the nucleocapsid core is designated as hepatitis B core antigen. The antigens in the outer surface are called as hepatitis B virus surface antigens. Core antigens are localized within the nuclei whereas the surface antigens are present in the cytoplasm of the infected cells. Antibodies to surface antigens appear in circulation at an early stage of infection whereas the antibodies to the core antigens are detected after several weeks. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human 
1 ml more info 14 days
€374,40 Add to cart -
HBcAg Polyclonal
Description Hepatitis B virus is spherical in shape with a diameter of 42 nm. It contains a 27 nm partially double stranded DNA core enclosed within a lipoprotein coat. The antigenic activity of the nucleocapsid core is designated as hepatitis B core antigen. The antigens in the outer surface are called as hepatitis B virus surface antigens. Core antigens are localized within the nuclei whereas the surface antigens are present in the cytoplasm of the infected cells. Antibodies to surface antigens appear in circulation at an early stage of infection whereas the antibodies to the core antigens are detected after several weeks. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€163,80 Add to cart -
HBsAg [A10F1]
Description Hepatitis B virus causes type B hepatitis and it belongs to hepadnavirus family. It is spherical in shape with a diameter of 42 nm. It contains a 27 nm partially double stranded DNA core enclosed within a lipoprotein coat. The antigenic activity of the nucleocapsid core is designated as hepatitis B core antigen. The antigens in the outer surface are called as hepatitis B virus surface antigens. Core antigens are localized within the nuclei whereas the surface antigens are present in the cytoplasm of the infected cells. Antibodies to surface antigens appear in circulation at an early stage of infection whereas the antibodies to the core antigens are detected after several weeks. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity HBV
1 ml more info 14 days
€361,40 Add to cart
