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OLIG2 [EP112]
Description Oligodendrocyte transcription factor 2 (OLIG2) is a transcription factor with basic helix-loop-helix (bHLH) domains that have fundamental roles in neuronal and glial production. It is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. As a result, it plays a critical role in motor neuron and oligodendrocyte fate specification during development. It cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. The expression of OLIG2 is normally restricted to neural tissues; however, overexpression of OLIG2 has been shown in patients with precursor T-cell lymphoblastic lymphoma/leukemia. OLIG2 is a useful marker for the identification of oligodendroglioma. The expression level of OLIG2 in anaplastic oligodendrogliomas was more uniform and intense than in other glial tumors. Several primary brain tumors with clear cell histology, oligodendroglioma (OG), clear cell epen Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human 
1 ml more info 
14 days 
€494,00 Add to cart -
OLIG2 [EP112]
Description Oligodendrocyte transcription factor 2 (OLIG2) is a transcription factor with basic helix-loop-helix (bHLH) domains that have fundamental roles in neuronal and glial production. It is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. As a result, it plays a critical role in motor neuron and oligodendrocyte fate specification during development. It cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. The expression of OLIG2 is normally restricted to neural tissues; however, overexpression of OLIG2 has been shown in patients with precursor T-cell lymphoblastic lymphoma/leukemia. OLIG2 is a useful marker for the identification of oligodendroglioma. The expression level of OLIG2 in anaplastic oligodendrogliomas was more uniform and intense than in other glial tumors. Several primary brain tumors with clear cell histology, oligodendroglioma (OG), clear cell epen Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart -
Ornithine Decarboxylase-1 (ODC-1) [ODC1/485]
Description Belongs to the Orn/Lys/Arg decarboxylase class-II family. Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Rat, Bovine
1 ml more info 14 days
€361,40 Add to cart -
Ornithine Decarboxylase-1 (ODC-1) [ODC1/485]
Description Belongs to the Orn/Lys/Arg decarboxylase class-II family. Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Rat, Bovine
7 ml more info 14 days
€187,20 Add to cart -
Osteocalcin/BGLAP [G5]
Description Bone γ-carboxyglutamic acid (Gla) protein, known as BGLAP, BGP or osteocalcin, is an abundant, non-collagenous protein component of bone that is produced by osteoblasts. In mice, osteocalcin is composed of a cluster of 3 genes known as OG1, OG2 and ORG, all of which can be found within a 23 Kb span of genomic DNA. Human osteocalcin is a highly conserved, 46-50 amino acid, single chain protein that contains 3 vitamin K-dependent γ-carboxyglutamic acid residues. Osteocalcin appears transiently in embryonic bone at the time of mineral deposition, where it binds to hydroxyapatite in a calcium-dependent manner. In addition, osteocalcin is one of the most abundant, non-collagenous proteins found in mineralized adult bone. Genetic variation at the osteocalcin locus on chromosome 1q22 impacts postmenopause bone mineral density (BMD) levels and may predispose some women to osteoporosis. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€361,40 Add to cart -
Osteonectin/SPARC/BM40 [MD18R]
Description Bone matrix consists of collagen and non-collagenous proteins. Osteonectin, a 32-kD calcium-binding glycoprotein, is found in a variety of cell types, which include osteoblastic epithelial cells and fibroblasts. In bone tissue, this glycoprotein is present in active osteoblasts and young osteocytes, and it is involved in the early steps of mineralization of skeletal tissue. Osteonectin is a recognized differentiation marker of normal osteogenic cells.The latter represents about 10% of the total protein content of bone. Osteonectin is one of the non-collagenous components and is bone-specific due to its biochemical properties. Osteonectin is a useful biochemical marker for bone-related tumors. Thus, osteonectin antibody can be used to demonstrate the presence of osteonectin in active osteoblasts and osteoprogenitor cells as well as in young osteocytes. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€401,70 Add to cart -
Osteonectin/SPARC/BM40 [MD18R]
Description Bone matrix consists of collagen and non-collagenous proteins. Osteonectin, a 32-kD calcium-binding glycoprotein, is found in a variety of cell types, which include osteoblastic epithelial cells and fibroblasts. In bone tissue, this glycoprotein is present in active osteoblasts and young osteocytes, and it is involved in the early steps of mineralization of skeletal tissue. Osteonectin is a recognized differentiation marker of normal osteogenic cells.The latter represents about 10% of the total protein content of bone. Osteonectin is one of the non-collagenous components and is bone-specific due to its biochemical properties. Osteonectin is a useful biochemical marker for bone-related tumors. Thus, osteonectin antibody can be used to demonstrate the presence of osteonectin in active osteoblasts and osteoprogenitor cells as well as in young osteocytes. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart -
Osteopontin (EPR21139-316]
Description Osteopontin, also known as Phosphoprotein 1 (SPP1), is an acidic, calcium-binding glycol-phosphoprotein of 44 to 66 kDa, depending on species and cell type. Osteopontin interacts with integrins and CD44. It has been shown to be multifunctional in cell migration, cell survival, inhibition of calcification, regulation of immune cell function, development and regeneration of skeletal muscle, and control of tumor cell phenotype. Osteopontin is found in all body fluids and secreted by osteoclasts, macrophages, cardiac fibroblasts, and activated T cells. Immunohistochemical analysis shows that Osteopontin is widely expressed in many types of cells including epithelial cells of the gastrointestinal tract, gall bladder, pancreas, urinary and reproductive tracts, lung, breast, salivary glands, and sweat glands. Osteopontin is overexpressed in a variety of human malignancies, including breast, lung, ovarian, gastric, hepatocellular, and prostate carcinomas, mesothelioma, and melanoma. It was pro Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€494,00 Add to cart -
Osteopontin (EPR21139-316]
Description Osteopontin, also known as Phosphoprotein 1 (SPP1), is an acidic, calcium-binding glycol-phosphoprotein of 44 to 66 kDa, depending on species and cell type. Osteopontin interacts with integrins and CD44. It has been shown to be multifunctional in cell migration, cell survival, inhibition of calcification, regulation of immune cell function, development and regeneration of skeletal muscle, and control of tumor cell phenotype. Osteopontin is found in all body fluids and secreted by osteoclasts, macrophages, cardiac fibroblasts, and activated T cells. Immunohistochemical analysis shows that Osteopontin is widely expressed in many types of cells including epithelial cells of the gastrointestinal tract, gall bladder, pancreas, urinary and reproductive tracts, lung, breast, salivary glands, and sweat glands. Osteopontin is overexpressed in a variety of human malignancies, including breast, lung, ovarian, gastric, hepatocellular, and prostate carcinomas, mesothelioma, and melanoma. It was pro Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart -
Osteopontin Polyclonal
Description Osteopontin, also known as Phosphoprotein 1 (SPP1), is an acidic, calcium-binding glycol-phosphoprotein of 44 to 66 kDa, depending on species and cell type. Osteopontin interacts with integrins and CD44. It has been shown to be multifunctional in cell migration, cell survival, inhibition of calcification, regulation of immune cell function, development and regeneration of skeletal muscle, and control of tumor cell phenotype. Osteopontin is found in all body fluids and secreted by osteoclasts, macrophages, cardiac fibroblasts, and activated T cells. Immunohistochemical analysis shows that Osteopontin is widely expressed in many types of cells including epithelial cells of the gastrointestinal tract, gall bladder, pancreas, urinary and reproductive tracts, lung, breast, salivary glands, and sweat glands. Osteopontin is overexpressed in a variety of human malignancies, including breast, lung, ovarian, gastric, hepatocellular, and prostate carcinomas, mesothelioma, and melanoma. It was pro Host Rabbit Application ELISA, Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat 
1 ml more info 14 days
€374,40 Add to cart
