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ACTH [2F6]
Description ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).ĀIt also may react with other tumors (e.g. some small cell carcinomas of the lung) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse, Rat -
ACTH [2F6]
Description ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).ĀIt also may react with other tumors (e.g. some small cell carcinomas of the lung) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse, Rat -
ACTH [AH26]
Description ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).ĀIt also may react with other tumors (e.g. some small cell carcinomas of the lung) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse, Rat -
ACTH [AH26]
Description ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).ĀIt also may react with other tumors (e.g. some small cell carcinomas of the lung) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse, Rat -
Actin alpha Sarcomeric [5C5]
Description Actin is a cytoskeletal protein that regulates cell motility, secretion, phagocytosis and cytokinesis. The NH2-terminal of actin may function as antigen. This terminal may also modulate actin interactions and may associate with proteins such as myosin. This antibody is specific for α-skeletal and α-cardiac muscle actins as characterized by ELISA, immunoblot and immunohistochemistry. The antibody shows wide species cross reactivity with tissue from human, sheep, bovine, rabbit, guinea pig, rat, frog, snake, and carp. However, it does not react with smooth muscle tissue. (Shipping Cost: €200.00) Host Mouse Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Sheep, Bovine, Rabbit, Guinea Pig, Rat, Frog, Snake, Carp -
Actin alpha Sarcomeric [5C5]
Description Actin is a cytoskeletal protein that regulates cell motility, secretion, phagocytosis and cytokinesis. The NH2-terminal of actin may function as antigen. This terminal may also modulate actin interactions and may associate with proteins such as myosin. This antibody is specific for α-skeletal and α-cardiac muscle actins as characterized by ELISA, immunoblot and immunohistochemistry. The antibody shows wide species cross reactivity with tissue from human, sheep, bovine, rabbit, guinea pig, rat, frog, snake, and carp. However, it does not react with smooth muscle tissue. (Shipping Cost: €200.00) Host Mouse Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Sheep, Bovine, Rabbit, Guinea Pig, Rat, Frog, Snake, Carp -
Actin Muscle Specific [HHF35]
Description This antibody recognizes all muscular actin isotypes. It labels myoepithelial, smooth muscle, skeletal, cardiac muscle cells and leiomyomas. It has been reported to react with pericytes and reactive myofibroblasts. Positive staining cells have been reported in some sarcomas, representing either myofibroblasts or pericytes components. Using this antibody with other myogenic markers such as smooth muscle a ctin, desmin and vimentin will be very helpful for differentiation of tumor from muscle origin. Clone HHF35 has been demonstrated to be reliable marker for soft tissue tumors with muscle differentiation, i.e. leiomyomas, leiomyosarcomas, and rhabdomyosarcomas. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human -
Actin Muscle Specific [HHF35]
Description This antibody recognizes all muscular actin isotypes. It labels myoepithelial, smooth muscle, skeletal, cardiac muscle cells and leiomyomas. It has been reported to react with pericytes and reactive myofibroblasts. Positive staining cells have been reported in some sarcomas, representing either myofibroblasts or pericytes components. Using this antibody with other myogenic markers such as smooth muscle a ctin, desmin and vimentin will be very helpful for differentiation of tumor from muscle origin. Clone HHF35 has been demonstrated to be reliable marker for soft tissue tumors with muscle differentiation, i.e. leiomyomas, leiomyosarcomas, and rhabdomyosarcomas. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human -
Actin Muscle Specific [MSA/953]
Description This antibody recognizes all muscular actin isotypes. It labels myoepithelial, smooth muscle, skeletal, cardiac muscle cells and leiomyomas. It has been reported to react with pericytes and reactive myofibroblasts. Positive staining cells have been reported in some sarcomas, representing either myofibroblasts or pericytes components. Using this antibody with other myogenic markers such as smooth muscle a ctin, desmin and vimentin will be very helpful for differentiation of tumor from muscle origin. Clone HHF35 has been demonstrated to be reliable marker for soft tissue tumors with muscle differentiation, i.e. leiomyomas, leiomyosarcomas, and rhabdomyosarcomas. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Rabbit, Rat -
Actin Muscle Specific MSA/953]
Description This antibody recognizes all muscular actin isotypes. It labels myoepithelial, smooth muscle, skeletal, cardiac muscle cells and leiomyomas. It has been reported to react with pericytes and reactive myofibroblasts. Positive staining cells have been reported in some sarcomas, representing either myofibroblasts or pericytes components. Using this antibody with other myogenic markers such as smooth muscle a ctin, desmin and vimentin will be very helpful for differentiation of tumor from muscle origin. Clone HHF35 has been demonstrated to be reliable marker for soft tissue tumors with muscle differentiation, i.e. leiomyomas, leiomyosarcomas, and rhabdomyosarcomas. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Rabbit, Rat