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B-type Natriuretic Peptide, BNP-32, human
Description B-type (Brain) natriuretic peptide (BNP) is a 32 amino acid hormone initially isolated from the porcine brain, but mainly produced by the heart ventricles. It is released from a prepro-hormone after cleavage of a signal peptide and further processing by a protease with a conserved recognition sequence (RXXR-S). This cleavage generated NT-proBNP (76aa) and the biologically active 32aa BNP-32, which are secreted in blood in equimolar concentrations. | BNP-32 is secreted by cardiomyocytes in response to myocardial stretch and overload resulting from hypervolaemia and increased blood pressure. It is known to oppose the renin-angiotensin-aldosterone system and exert vasodilatory effects. This 32 amino acid peptide contains a 17 amino acid ring structure that is common to all natriuretic peptides. (Shipping Cost: €35.00) 
0 mg more info 
3 days 
€240,00 Add to cart -
Calcitonin Gene Related Peptide, CGRP (alpha), human
Description Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide produced by tissue specific processing of the calcitonin gene and is the major product in neural tissues. CGRP is released by motor neurons where it exerts both short and long term effects on skeletal muscle fibers. In addition, sensory neurons release CGRP to the surrounding vasculature where it is partly responsible for local vasodilation following muscle contraction. CGRP acts through G protein-coupled receptors whose presence and changes in function modulate the peptide's effects in various tissues. (Shipping Cost: €35.00)
0 mg more info 3 days
€154,00 Add to cart -
ω-Conotoxin GVIA
Description This peptide is a neurotoxin that blocks N-type calcium channels. (Shipping Cost: €35.00)
0 mg more info 3 days
€240,00 Add to cart -
Biotin-beta-Amyloid (1-42)
Description Aß (1-42), a major component of amyloid plaques, accumulates in neurons of Alzheimer’s disease brains. Biochemical analysis of the amyloid peptides isolated from Alzheimer’s disease brain indicates that Aß (1-42) is the principal species associated with senile plaque amyloids, while Aß (1-40) is more abundant in cerebrovascular amyloid deposit. This peptide is biotinylated at the N-terminus. (Shipping Cost: €35.00)
0 mg more info 3 days
€285,00 Add to cart -
[Cys26]-beta-Amyloid (1-42)
Description Subsitution of Ser 26 with Cys in Aβ1-42 allows the generation of the covalently linked Aβ42 homodimer. Dimerization can be reverted by adding a reducing agent. This Cys-containing mutant can be used as a model for aggregation studies. (Shipping Cost: €35.00)
0 mg more info 3 days
€245,00 Add to cart -
Endothelin 3, human, rat, mouse, rabbit
Description Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. This 21 residue peptide (ET-3) is a member of a family of potent vasoconstrictors namely, Endothelin and Sarafotoxin. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. ET-3 is a less potent vasoconstrictor than ET-1 also varying by 6 amino acids in sequence homology. (Shipping Cost: €35.00)
0 mg more info 3 days
€197,00 Add to cart -
Beta-Amyloid (1-40)-Lys(Biotin-LC)
Description This C-terminal biotinylated Aß(1-40) contains a 6-carbon long chain (LC) to provide more accesibility for avidin attachment. (Shipping Cost: €35.00)
0 mg more info 3 days
€588,00 Add to cart -
Biotin-Exendin 4
Description This peptide, Exendin-4, has a biotin on the N-terminus. Exendin-4, an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Exendin-4 shares a 53% sequence homology with GLP-1. Derived from Gila monster, Heloderma suspectum, Exendin-4 has a longer half life than GLP-1 in the plasma, thus making it a more potent insulinotropic agent. (Shipping Cost: €35.00)
0 mg more info 3 days
€384,00 Add to cart -
Beta-Amyloid (1-42) Peptide HCl salt
Description Aß (1-42), a major component of amyloid plaques, accumulates in neurons of Alzheimer’s disease brains. Biochemical analysis of the amyloid peptides isolated from Alzheimer’s disease brain indicates that Aß (1-42) is the principal species associated with senile plaque amyloids, while Aß (1-40) is more abundant in cerebrovascular amyloid deposit. The HCl salt form of Aß (1-42) takes the ß-structure within a few hours in PBS and aggregates (Shipping Cost: €35.00)
0 mg more info 3 days
€269,00 Add to cart -
PACAP (6-38), amide, human, ovine, rat
Description This peptide is a potent antagonist of PACAP 38 and is much more potent and selective than PACAP (6-27) in the inhibition of PACAP-27 stimulated pituitary adenylate cyclase. The Ki values for the inhibition of the enzyme are 7nM and 150 nM, respectively. (Shipping Cost: €35.00)
0 mg more info 3 days
€171,00 Add to cart
