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  • Article number: AS-64356-025
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    [Lys(Me2)4]-Histone H3 (1-21)-GGK(Biotin)

    Description This peptide is Histone H3 amino acid residues 1 to 21 di-methylated at Lys-4 with a C-terminal GG linker followed by a biotinylated lysine. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form. (Shipping Cost: €35.00)
    Unit 0 mg
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    Normal leadtime 3 days
    Calculated total €114,00 
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  • Article number: AS-64440-025
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    Histone H3 (21-44)-GK(Biotin)

    Description This peptide is derived from Histone H3 21-44 amino acids, with additional glycine and lysine at the C-terminus with lysine biotinylated and used as substrate in methylation assays. (Shipping Cost: €35.00)
    Unit 0 mg
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    Normal leadtime 3 days
    Calculated total €114,00 
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  • Article number: AS-64358-025
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    [Lys(Me1)9]-Histone H3 (1-21)-GGK(Biotin)

    Description This peptide is Histone H3 amino acid residues 1 to 21 mono-methylated at Lys-9 with a C-terminal GG linker followed by a biotinylated lysine. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form. (Shipping Cost: €35.00)
    Unit 0 mg
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    Normal leadtime 3 days
    Calculated total €114,00 
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  • Article number: AS-22991-025
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    HCV Protease FRET Substrate (RET S1)

    Description This peptide is a HCV protease substrate incorporating an ester bond between residues P1 and P1. Due to ready transesterification of the scissile bond to the acyl-enzyme intermediate, this substrate shows very high kcat/Km values, enabling detection of activity with subnanomolar nonstructural protein 3 (NS3 protease) concentrations. It is widely used for the continuous assay of NS3 protease activity. Substrate cleavage is proportional to the enzyme concentration with a detection limit for NS3 between 1 nM and 250 pM. Upon cleavage of this substrate, fluorescence can be monitored at Abs/Em = 355/500 nm. (Shipping Cost: €35.00)
    Unit 0 mg
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    Normal leadtime 3 days
    Calculated total €189,00 
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  • Article number: AS-64367-025
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    [Lys(Me3)27]-Histone H3 (21-44)-GK(Biotin)

    Description This peptide is Histone H3 amino acid residues 21 to 44 tri-methylated at Lys-27 with an additional C-terminal glycine followed by a biotinylated lysine. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form. (Shipping Cost: €35.00)
    Unit 0 mg
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    Normal leadtime 3 days
    Calculated total €114,00 
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  • Article number: AS-64441-025
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    [Lys(Me3)36]-Histone H3 (21-44)-GK(Biotin)

    Description This is a Histone 3 peptide trimethylated at lysine 36. It's role has been indicative of defining exons, as certain nucleosome-enriched exons are observed to be enriched in some histone modifications. It is belived that this pattern of modification as seen with this H3K36me3 peptide, influences alternative splicing, perhaps by signaling effector proteins to mark particular exons for inclusion in the final transcript as they exit the RNA Polymerase II complex. It has also been shown in yeast that H3K36me3 gets deposited on histones as they are displaced by RNA polymerase II (RNAPII) during transcription. H3K36me3 then serves as a mark for HDACs to bind and deacetylate the histones. (Shipping Cost: €35.00)
    Unit 0 mg
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    Normal leadtime 3 days
    Calculated total €114,00 
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  • Article number: AS-64363-025
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    [Lys(Ac)9/14]-Histone H3 (1-21)-GGK(Biotin)

    Description This peptide is Histone H3 amino acid residues 1 to 21 acetylated at Lys-9 and Lys-14 with a C-terminal GG linker followed by a biotinylated lysine. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form. (Shipping Cost: €35.00)
    Unit 0 mg
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    Normal leadtime 3 days
    Calculated total €114,00 
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  • Article number: AS-22859
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    Endothelin 1, human, porcine, bovine, mouse, rat

    Description ET-1 is a potent vasoconstrictor peptide derived from endothelial cells. It plays a role in regulation of cardiovascular functions. The binding of ET-1 to G-protein coupled receptor triggers a signal transduction cascade leading to activation of the protein kinase C (PKC). PKC inhibitor potentially reverses the up regulation of ET-1. The enhanced ET-1 expression associated with the activation of PKC occurs in early diabetes. (Shipping Cost: €35.00)
    Unit 0 mg
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    Normal leadtime 3 days
    Calculated total €184,00 
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  • Article number: AS-25381
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    Beta-Amyloid Peptide (1-42), mouse, rat

    Description This is amino acids 1 to 42 fragment of mouse and rat beta-amyloid. It differs from human beta-amyloid by three amino acid residues: Arg5, Tyr10, and His13 residues in human beta-amyloid correspond to Gly5, Phe10, and Arg13 in mice and rat sequence. (Shipping Cost: €35.00)
    Unit 0 mg
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    Normal leadtime 3 days
    Calculated total €347,00 
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  • Article number: AS-20761
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    Glucagon-Like Peptide 1, GLP-1 (7-37) human, mouse, rat, bovine, guinea pig

    Description GLP-1 (7-37) is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of proglucagon. Both GLP-1 (7-36) and GLP-1 (7-37) play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. Although GLP-1 (7-37) is bioactive, it is available in lesser amounts than GLP-1 (7-36) and is not amidated. (Shipping Cost: €35.00)
    Unit 0 mg
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    Normal leadtime 3 days
    Calculated total €154,00 
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