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MyoD1 (Rhabdomyosarcoma Marker) [5.8A]
Description Recognizes a phosphor-protein of 45kDa, identified as MyoD1. The epitope of this antibody maps between amino acid 180-189 in the C-terminal of mouse MyoD1 protein. It does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse, Rat, Chicken 
1 ml more info 
14 days 
€361,40 Add to cart -
Myogenin (MyF4) [F5D]
Description Myogenic factors are transcription factors consisting of an amino acid-rich region and a helix-loop-helix (HLH) structure, which can promote muscle development and maintain muscle-specific gene expression by transactivation. Myogenin, one of the myogenic regulatory factors, plays a key role in determining the commitment and differentiation of primitive mesenchymal cells into skeletal muscle. The expression of Myogenin is restricted to cells of skeletal muscle origin, but it is not detected in adult skeletal muscles. It is therefore considered to be an extremely reliable and specific marker for diagnosing rhabdomyosarcomas. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
Myogenin (MyF4) [F5D]
Description Myogenic factors are transcription factors consisting of an amino acid-rich region and a helix-loop-helix (HLH) structure, which can promote muscle development and maintain muscle-specific gene expression by transactivation. Myogenin, one of the myogenic regulatory factors, plays a key role in determining the commitment and differentiation of primitive mesenchymal cells into skeletal muscle. The expression of Myogenin is restricted to cells of skeletal muscle origin, but it is not detected in adult skeletal muscles. It is therefore considered to be an extremely reliable and specific marker for diagnosing rhabdomyosarcomas. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€234,00 Add to cart -
Myosin Skeletal Heavy Chain Fast/MYH1 [MY-32]
Description Myosin, a 480kD protein that interacts with actin in muscle and non muscle cells, is composed of 2 identical heavy chains (about 200kD each) and 4 light chains (about 20kD each). Conventional myosin molecules consist of two major regions: tail (rod) and globular heads; they aggregate into filaments through the tail region and interact with actin and with adenosine triphosphate (ATP) through the head region. Multiple forms of myosin heavy chains exist in skeletal, smooth and cardiac muscle and in non-muscle tissues. A spectrum of skeletal muscle fiber types is found in adult skeletal muscles. The two major skeletal muscle fiber types are type I (slow-twitch) and type II (fast-twitch). Skeletal muscle type II fibers can be further subdivided into types IIa (fast red) and IIb (fast white). (Shipping Cost: €200.00) Host Mouse Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat, Rabbit, Chicken, Guinea Pig, Bovine
1 ml more info 14 days
€429,00 Add to cart -
Myosin Skeletal Heavy Chain Slow/MYH7 [NOQ7.5.4D]
Description Myosin, a 480kD protein that interacts with actin in muscle and non muscle cells, is composed of 2 identical heavy chains (about 200kD each) and 4 light chains (about 20kD each). Conventional myosin molecules consist of two major regions: tail (rod) and globular heads; they aggregate into filaments through the tail region and interact with actin and with adenosine triphosphate (ATP) through the head region. Multiple forms of myosin heavy chains exist in skeletal, smooth and cardiac muscle and in non-muscle tissues. A spectrum of skeletal muscle fiber types is found in adult skeletal muscles. The two major skeletal muscle fiber types are type I (slow-twitch) and type II (fast-twitch). Type I muscle fibers are more efficient over long periods of time. They are mainly used for postural maintenance (such has holding the head upright), or endurance exercises (like marathon running). (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Radioimmunoassay (RIA), Western Blot (WB) Reactivity Human, Mouse, Rat, Rabbit, Chicken, Guinea Pig, Bovine, Sheep, Goat, Hamster, Cat, Dog (Canine),Pig (Porcine)
1 ml more info 14 days
€429,00 Add to cart -
Myosin Smooth Muscle Heavy Chain [SMMS1]
Description SMMS-1 is an antibody to smooth muscle myosin, heavy chain that reacts with human visceral and vascular smooth muscle cells. The antibody also reacts with human myoepithelial cells. It is very helpful in distinguishing between benign sclerosing breast lesions and infiltrating carcinomas in difficult cases since it strongly stains the myoepithelial layer in the benign lesions while it is negative in the infiltrating carcinomas. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
Myosin Smooth Muscle Heavy Chain [SMMS1]
Description SMMS-1 is an antibody to smooth muscle myosin, heavy chain that reacts with human visceral and vascular smooth muscle cells. The antibody also reacts with human myoepithelial cells. It is very helpful in distinguishing between benign sclerosing breast lesions and infiltrating carcinomas in difficult cases since it strongly stains the myoepithelial layer in the benign lesions while it is negative in the infiltrating carcinomas. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
Napsin A [NAPSA/3308]
Description Napsin A is an aspartic proteinase that belongs to the peptidase A1 family and plays a role in pneumocyte surfactant processing. In normal tissue, Anti-Napsin A specifically labels type II pneumocytes in adult lung and epithelial cells in kidney tissues. In abnormal tissues, Napsin A is strongly positive in over 80% of primary lung adenocarcinomas and 79% of renal cell carcinoma by immunohistochemistry. Napsin A is a useful marker for lung adenocarcinoma. The combined use of Napsin A and thyroid transcription factor (TTF) improves the sensitivity and specificity for identification of pulmonary adenocarcinoma (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
Napsin A [NAPSA/3308]
Description Napsin A is an aspartic proteinase that belongs to the peptidase A1 family and plays a role in pneumocyte surfactant processing. In normal tissue, Anti-Napsin A specifically labels type II pneumocytes in adult lung and epithelial cells in kidney tissues. In abnormal tissues, Napsin A is strongly positive in over 80% of primary lung adenocarcinomas and 79% of renal cell carcinoma by immunohistochemistry. Napsin A is a useful marker for lung adenocarcinoma. The combined use of Napsin A and thyroid transcription factor (TTF) improves the sensitivity and specificity for identification of pulmonary adenocarcinoma (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
NeuN [A60]
Description NeuN antibody specifically recognizes the DNA-binding, neuron-specific protein NeuN, which is present in most CNS and PNS neuronal cell types of all vertebrates tested. NeuN protein distributions are apparently restricted to neuronal nuclei, perikarya and some proximal neuronal processes in both fetal and adult brain although, some neurons fail to be recognized by NeuN at all ages: INL retinal cells, Cajal-Retzius cells, Purkinje cells, inferior olivary and dentate nucleus neurons, and sympathetic ganglion cells are examples. Immunohistochemically detectable NeuN protein first appears at developmental timepoints that correspond with the withdrawal of the neuron from the cell cycle and/or with the initiation of terminal differentiation of the neuro. Immunoreactivity appears around E9.5 in the mouse neural tube and is extensive throughout the developing nervous system by E12.5. Strong nuclear staining suggests a nuclear regulatory protein function; however, no evidence currently exists a Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Avian, Chicken, Ferret, Human, Mouse,Pig (Porcine), Rat, Salamander
1 ml more info 14 days
€361,40 Add to cart
