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200 kDa Neurofilament antibody
Description Mouse monoclonal 200 kDa Neurofilament antibody (Shipping Cost: €205.00) Host Mouse Application Immunohistochemistry on frozen sections (IHC-Fs),Immunohistochemistry on paraffin sections (IHC-P),Western Blot (WB) Reactivity Bovine,Dog (Canine),Chicken,Guinea Pig,Human,Monkey,Mouse,Rabbit,Rat,Sheep,Xenopus Specificity Reacts exclusively with the phosphorylated isoform of the 200 kD neurofilament protein -
Reticulon 1A/B antibody
Description Mouse monoclonal Reticulon 1A/B antibody (Shipping Cost: €205.00) Host Mouse Application Flow Cytometry (FC),Immunohistochemistry (IHC),Immunohistochemistry on frozen sections (IHC-Fs),Immunohistochemistry on paraffin sections (IHC-P),Western Blot (WB) Reactivity Human,Monkey,Rabbit Specificity Recognizes an epitope located within the region of amino acids 421-589 of the neuro-endocrine specific protein Reticulon-1A (NSP-A), which is also present in the N-terminal part of Reticulon-1B (NSP-B) -
Reticulon 1A/B antibody
Description Mouse monoclonal Reticulon 1A/B antibody (Shipping Cost: €205.00) Host Mouse Application Flow Cytometry (FC),Immunohistochemistry (IHC),Immunohistochemistry on frozen sections (IHC-Fs),Immunohistochemistry on paraffin sections (IHC-P),Western Blot (WB) Reactivity Human,Monkey,Rabbit Specificity Recognizes an epitope located within the region of amino acids 421-589 of the neuro-endocrine specific protein Reticulon-1A (NSP-A), which is also present in the N-terminal part of Reticulon-1B (NSP-B) -
ERBB2 antibody
Description Mouse monoclonal ERBB2 antibody (Shipping Cost: €205.00) Host Mouse Application Immunohistochemistry on frozen sections (IHC-Fs),Immunohistochemistry on paraffin sections (IHC-P),Immunoprecipitation (IP),Western Blot (WB) Reactivity Human,Monkey,Mouse,Rat Specificity Reacts equally well with the wild type as well as the mutant (oncogenic) form of the c-erbB-2/HER-2/neu protein, but preferentially recognizes the unphosphorylated form of this protein -
Smoothelin antibody
Description Mouse monoclonal Smoothelin antibody (Shipping Cost: €205.00) Host Mouse Application Immunohistochemistry on frozen sections (IHC-Fs),Immunohistochemistry on paraffin sections (IHC-P),Western Blot (WB) Reactivity Dog (Canine),Chicken,Cat,Human,Monkey,Swine Specificity Reacts with the 59 kDa and 100 kDa protein, corresponding to smoothelin A and B, respectively, which are exclusively found in smooth muscle cells -
Vimentin antibody
Description Mouse monoclonal Vimentin antibody (Shipping Cost: €205.00) Host Mouse Application Flow Cytometry (FC),Immunohistochemistry (IHC),Immunohistochemistry on frozen sections (IHC-Fs),Immunohistochemistry on paraffin sections (IHC-P),Western Blot (WB) Reactivity Dog (Canine),Chicken,Goat,Hamster,Human,Monkey,Mouse,Rat,Swine,Zebrafish Specificity Reacts exclusively with vimentin, which is expressed in mesenchymal cells and mesenchymal derived tumors eg lymphoma, sarcoma and melanoma -
AFP [SPM334]
Description Alpha-fetoprotein (AFP) is the most abundant plasma protein found in the human fetus. It is thought to be the fetal form of serum albumin. AFP binds to copper, nickel, fatty acids and bilirubin and is found in monomeric, dimeric and trimeric forms. Alpha-Fetoprotein (AFP) is synthesized by the cells of the embryonic yolk sac, fetal liver and fetal intestinal tract. AFP levels decrease soon after birth. In abnormal tissues, expression of AFP has been demonstrated in hepatocellular carcinoma, hepatoid adenocarcinoma, germ cell tumors and particularly yolk sac tumor. The anti-AFP antibody may be useful for the identification of neoplastic liver diseases, yolk sac tumors and mixed germ cell tumors. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Monkey, Dog (Canine), Pig -
AFP [SPM334]
Description Alpha-fetoprotein (AFP) is the most abundant plasma protein found in the human fetus. It is thought to be the fetal form of serum albumin. AFP binds to copper, nickel, fatty acids and bilirubin and is found in monomeric, dimeric and trimeric forms. Alpha-Fetoprotein (AFP) is synthesized by the cells of the embryonic yolk sac, fetal liver and fetal intestinal tract. AFP levels decrease soon after birth. In abnormal tissues, expression of AFP has been demonstrated in hepatocellular carcinoma, hepatoid adenocarcinoma, germ cell tumors and particularly yolk sac tumor. The anti-AFP antibody may be useful for the identification of neoplastic liver diseases, yolk sac tumors and mixed germ cell tumors. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Monkey, Dog (Canine), Pig -
BAX [2D2]
Description Bax is a protein of the bcl-2 gene family. It promotes apoptosis by competing with bcl-2 proper. The Bax gene contains a small promoter element that complements a binding domain on the multi-faceted p53 tumor suppressor. Wild-type p53 has been demonstrated to upregulate the transcription of a chimeric reporter plasmid, utilizing the consensus promoter sequence of Bax approx. 50-fold over mutant p53. Mutations in this consensus sequence eliminate transcription of the reporter gene. Thus, it is likely that p53 promotes Bax’s apoptotic faculties in vivo as a primary transcription factor. Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells. Bax targets mitochondrial mem-branes, inducing mitochondrial damage and cell death in a caspase-independent manner. Bad plays a critical role in the Bax-mediated apoptosis pathway by dimerizing with BclxL, causing the displacement of Bax. The displacement of Bax allows apoptosis to proceed. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Monkey -
Bcl-2 [8C8]
Description Expression of Bcl-2α oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2α protein, whereas the normal or hyperplastic germinal centers are negative. This antibody recognizes a protein of 25-26kDa, identified as the bcl-2 α oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 α oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2 α protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Monkey,Pig (Porcine)