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  • Article number: 10R-CD35cHU
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    CD35 antibody

    Description Mouse monoclonal CD35 antibody (Shipping Cost: €205.00)
    Host Mouse
    Application Flow Cytometry (FC),Immunohistochemistry on frozen sections (IHC-Fs),Immunohistochemistry on paraffin sections (IHC-P),Immunoprecipitation (IP)
    Reactivity Baboon,Human,Monkey
    Concentration 0.1 mg/ml
    Specificity Human
    Unit 100 ug
    more info
    Normal leadtime 5-7 days
    Calculated total €225,00 
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  • Article number: 10R-M102a
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    Human Macrophage antibody

    Description Mouse monoclonal Macrophage L1 protein Calprotectin antibody (Shipping Cost: €205.00)
    Host Mouse
    Application Immunohistochemistry on frozen sections (IHC-Fs),Immunohistochemistry on paraffin sections (IHC-P)
    Reactivity Baboon,Cat,Dog (Canine),guinea Pig,Human,Monkey,Mouse,Pig (Porcine),Rat
    Concentration 0.2 mg/ml
    Unit 500 ul
    more info
    Normal leadtime 5-7 days
    Calculated total €0,01 
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  • Article number: MC0127
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    C5b9/TCC/MAC [aE11]

    Description The complement component proteins: C2, C3, C4 and C5 are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors, C3aR, C1R and C5aR, induces proinflammatory events, such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation and cellular chemotaxis. Activation of the complement system leads to the formation of C5b-9 terminal complex, and while C5b-9 can promote cell lysis, the sublytic assembly of C5b-9 on plasma membranes causes an opposite result and induces cell cycle activation and survival. C5b-9 can rescue oligodendrocytes from FAS-mediated apoptosis by regulating caspase-8 processing via PI 3-K signaling. C5b-9 may play a pro-inflammatory role in the acute phase of multiple sclerosis, but may also be neuroprotective during the chronic phase of the disease. (Shipping Cost: €200.00)
    Host Mouse
    Application ELISA, Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC)-F
    Reactivity Human, Horse,Pig (Porcine), Monkey, Baboon
    Unit 1 ml
    more info
    Normal leadtime 14 days
    Calculated total €429,00 
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  • Article number: MC0073
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    Macrophage L1 Protein [MAC387]

    Description Recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12kDa alpha chain and a 14kDa beta chain expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupfferā€™s cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria,
    Host Mouse
    Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC)
    Reactivity Human, Baboon, Monkey, Bovine,Pig (Porcine), Goat, Horse, Cat, Dog (Canine), Rabbit, Guinea Pig, Rat, Mouse
    Unit 1 ml
    more info
    Normal leadtime 14 days
    Calculated total €361,40 
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