You are here
-
160 kDa Neurofilament antibody
Description Mouse monoclonal 160 kDa Neurofilament antibody (Shipping Cost: €205.00) Host Mouse Application Immunohistochemistry on frozen sections (IHC-Fs),Immunohistochemistry on paraffin sections (IHC-P),Western Blot (WB) Reactivity Hamster,Human,Monkey,Xenopus Specificity Reacts exclusively with the phosphorylated isoform of the160 kD neurofilament protein -
160 kDa Neurofilament antibody
Description Mouse monoclonal 160 kDa Neurofilament antibody (Shipping Cost: €205.00) Host Mouse Application Immunohistochemistry on frozen sections (IHC-Fs),Immunohistochemistry on paraffin sections (IHC-P),Western Blot (WB) Reactivity Guinea Pig,Hamster,Human,Monkey,Rabbit,Xenopus Specificity Reacts exclusively with the phosphorylated isoform of the160 kD neurofilament protein -
Vimentin antibody
Description Mouse monoclonal Vimentin antibody (Shipping Cost: €205.00) Host Mouse Application Flow Cytometry (FC),Immunohistochemistry (IHC),Immunohistochemistry on frozen sections (IHC-Fs),Immunohistochemistry on paraffin sections (IHC-P),Western Blot (WB) Reactivity Dog (Canine),Chicken,Goat,Hamster,Human,Monkey,Mouse,Rat,Swine,Zebrafish Specificity Reacts exclusively with vimentin, which is expressed in mesenchymal cells and mesenchymal derived tumors eg lymphoma, sarcoma and melanoma -
NF-κB p65 [MD35R]
Description Transcription factors of the nuclear factor κ B (NF-κB)/Rel family play a pivotal role in inflammatory and immune responses. There are five family members in mammals: RelA, c-Rel, RelB, NF-κB1 (p105/p50), and NF-κB2 (p100/p52). Both p105 and p100 are proteolytically processed by the proteasome to produce p50 and p52, respectively. Rel proteins bind p50 and p52 to form dimeric complexes that bind DNA and regulate transcription. In unstimulated cells, NF-κB is sequestered in the cytoplasm by IκB inhibitory proteins. NF-κB-activating agents can induce the phosphorylation of IκB proteins, targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression. NIK and IKKα (IKK1) regulate the phosphorylation and processing of NF-κB2 (p100) to produce p52, which is then translocated to the nucleus. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat, Hamster, Monkey, Dog -
NF-κB p65 [MD35R]
Description Transcription factors of the nuclear factor κ B (NF-κB)/Rel family play a pivotal role in inflammatory and immune responses. There are five family members in mammals: RelA, c-Rel, RelB, NF-κB1 (p105/p50), and NF-κB2 (p100/p52). Both p105 and p100 are proteolytically processed by the proteasome to produce p50 and p52, respectively. Rel proteins bind p50 and p52 to form dimeric complexes that bind DNA and regulate transcription. In unstimulated cells, NF-κB is sequestered in the cytoplasm by IκB inhibitory proteins. NF-κB-activating agents can induce the phosphorylation of IκB proteins, targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression. NIK and IKKα (IKK1) regulate the phosphorylation and processing of NF-κB2 (p100) to produce p52, which is then translocated to the nucleus. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat, Hamster, Monkey, Dog