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CD44 (HCAM) [156-3C11]
Description CD44 is a cell-surface glycoprotein postulated to play a role in a variety of biological processes, including cell-to-cell and cell-to-matrix adhesion, lymphocyte homing and tumor cell metastasis. Several isoforms of CD44 have been identified in human cells, and the genesis of some of these isoforms has been attributed to alternative splicing. Understanding of mechanisms regulating CD44 alternative splicing may provide insights into diverse processes, including tumor-cell metastasis and lymphocyte homing. CD44 is widely expressed on many types of cells with mesodermal and hematopoietic origin, epithelial cells and a variety of tumors derived from these cells. Loss of CD44 expression has been linked to tumor invasion, metastasis and progression in carcinomas of breast, prostate, lung, ovary and malignant melanoma. Expressed on approximately 90% of lymphocytes, monocytes, granulocytes, and, in lower amounts on thymocytes, fibroblasts, and erythrocytes. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Baboon, African green Monkey (Chlorocebus) 
7 ml more info 
14 days 
€187,20 Add to cart -
CD74 [LN-2]
Description Cluster of Differentiation 74 (CD74) is a type II transmembrane protein. In normal tissues, CD74 is expressed in B cells, monocytes, macrophages, Langerhans cells, dendritic cells, subsets of activated T cells, and thymic epithelium. Under inflammatory conditions, CD74 expression may be observed in endothelial and certain epithelial cells. CD74 expression has been observed in ~90% of B-cell cancers evaluated, as well as the majority of cell lines derived from these cancers.CD74 is a marker for distinguishing atypical fibroxanthoma from malignant fibrous histiocytoma, and it is also a useful marker for distinguishing leiomyosarcoma from leiomyoma. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Baboon, Mouse
1 ml more info 14 days
€361,40 Add to cart -
CD74 [LN-2]
Description Cluster of Differentiation 74 (CD74) is a type II transmembrane protein. In normal tissues, CD74 is expressed in B cells, monocytes, macrophages, Langerhans cells, dendritic cells, subsets of activated T cells, and thymic epithelium. Under inflammatory conditions, CD74 expression may be observed in endothelial and certain epithelial cells. CD74 expression has been observed in ~90% of B-cell cancers evaluated, as well as the majority of cell lines derived from these cancers.CD74 is a marker for distinguishing atypical fibroxanthoma from malignant fibrous histiocytoma, and it is also a useful marker for distinguishing leiomyosarcoma from leiomyoma. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Baboon, Mouse
7 ml more info 14 days
€187,20 Add to cart -
Macrophage L1 Protein [MAC387]
Description Recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12kDa alpha chain and a 14kDa beta chain expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupfferā€™s cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria, Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Baboon, Monkey, Bovine,Pig (Porcine), Goat, Horse, Cat, Dog (Canine), Rabbit, Guinea Pig, Rat, Mouse
1 ml more info 14 days
€361,40 Add to cart -
Monoclonal antibody to monkey CD3 (clone FN-18)
Description The monoclonal antibody to monkey CD3 (clone FN-18) was first described in 1986. The FN-18 antibody can be used in immunohistochemical staining of frozen tissues, flow cytometric analysis and intracellular staining. Further, the antibody is able to stimulate rhesus macaque PBMC. The FN-18 antibody has been reported to cross react with rhesus macaque, cynomolgus monkey and baboon CD3. Other available formats: biotin labeled (cat. no. CT162) and FITC labeled (cat. no. CT163). (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application Flow cytometry (FC),Immunohistochemistry on frozen sections (IHC-Fs) Reactivity Rhesus Macaque,Cynomolgus Monkey,Baboon
0 mg more info 8 days
€440,00 Add to cart -
Monoclonal antibody to monkey CD3 biotin (clone FN-18)
Description The monoclonal antibody to monkey CD3 (clone FN-18) was first described in 1986. The FN-18 antibody can be used in flow cytometric analysis. The FN-18 antibody has been reported to cross react with rhesus macaque, cynomolgus macaque and baboon CD3. Other available formats: unconjugated (cat. no.CT161) and FITC labeled (cat. no.CT163). (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application Flow cytometry (FC) Reactivity Rhesus Macaque,Cynomolgus Monkey,Baboon Conjugate Biotin
50 ug more info 8 days
€385,00 Add to cart -
Monoclonal antibody to monkey CD3 FITC (clone FN-18)
Description The monoclonal antibody to monkey CD3 (clone FN-18) was first described in 1986. The FN-18 antibody can be used in flow cytometric analysis. The FN-18 antibody has been reported to cross react with rhesus macaque, cynomolgus macaque and baboon CD3. Other available formats: unconjugated (cat. no. CT161) and biotin labeled (cat. no. CT162). (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application Flow cytometry (FC) Reactivity Rhesus Macaque,Cynomolgus Monkey,Baboon Conjugate FITC
50 ug more info 8 days
€385,00 Add to cart
