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FOXO1 antibody
Description Purified Polyclonal FOXO1 antibody (Shipping Cost: €205.00) Host Rabbit Application Western Blot (WB),Immunohistochemistry (IHC),Immunofluorescence (IF),Immunocytochemistry (ICC),Chromatin Immunoprecipitation (ChIP) Reactivity Bovine,Monkey,Pig (Porcine) Specificity Recognizes endogenous levels of FOXO1 protein -
Cyclin A1/2 antibody
Description Purified Polyclonal Cyclin A1/2 antibody (Shipping Cost: €205.00) Host Rabbit Application Western Blot (WB),Immunohistochemistry (IHC),Immunofluorescence (IF),Immunocytochemistry (ICC),Chromatin Immunoprecipitation (ChIP) Reactivity Mouse,Rat,Bovine,Chicken,Rabbit Specificity Recognizes endogenous levels of Cyclin A1/2 protein -
Histone H2B antibody
Description Purified Polyclonal Histone H2B antibody (Shipping Cost: €205.00) Host Rabbit Application Western Blot (WB),Immunohistochemistry (IHC),Immunofluorescence (IF),Immunocytochemistry (ICC),Chromatin Immunoprecipitation (ChIP) Reactivity Mouse,Bovine,Cat,Monkey Specificity Recognizes endogenous levels of Histone H2B protein -
NF kappaB p65 antibody
Description Purified Polyclonal NF kappaB p65 antibody (Shipping Cost: €205.00) Host Rabbit Application Western Blot (WB),Immunohistochemistry (IHC),Immunofluorescence (IF),Immunocytochemistry (ICC),Chromatin Immunoprecipitation (ChIP) Reactivity Mouse,Rat,Bovine,Pig (Porcine) Specificity Recognizes endogenous levels of NF-kappaB p65 protein -
GATA3 [MD22R]
Description GATA-3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This 50kD anuclear protein regulates the development and subsequent maintenance of a variety of human tissues, including hematopoietic cells, skin, kidney, mammary gland, and the central nervous system. Among several other roles, GATA-3 involved in luminal cell differentiation in the mammary gland and appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 is associated with the expression of estrogen receptor-alpha (ER) in breast cancer. GATA-3 has been shown to be a novel marker for bladder cancer. The study demonstrated that GATA-3 stained 67% of urothelial Carcinomas, but none of prostate or renal carcinomas. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Chromatin Immunoprecipitation (ChIP), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human -
GATA3 [MD22R]
Description GATA-3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This 50kD anuclear protein regulates the development and subsequent maintenance of a variety of human tissues, including hematopoietic cells, skin, kidney, mammary gland, and the central nervous system. Among several other roles, GATA-3 involved in luminal cell differentiation in the mammary gland and appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 is associated with the expression of estrogen receptor-alpha (ER) in breast cancer. GATA-3 has been shown to be a novel marker for bladder cancer. The study demonstrated that GATA-3 stained 67% of urothelial Carcinomas, but none of prostate or renal carcinomas. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Chromatin Immunoprecipitation (ChIP), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human -
MCM2 [MD32R]
Description Minichromosome maintenance protein 2 (MCM2), also known as DNA replication licensing factor MCM2, is a member of the MCM family that regulates mammalian DNA replication. This family is composed of six related subunits, called the hexameric MCM2-7 complex, that are conserved in all eukaryotes. It functions as a replicative helicase, the molecular motor that both unwinds duplex DNA and powers fork progression during DNA replication. MCM2 acts as a factor to license DNA for one and only one round of replication per cell cycle. In the cell cycle, levels of the MCM family gradually increase in a variable manner from G0 into the G1/S phase. In the G0 stage, the amounts of MCM2 and MCM5 proteins are much lower than that of MCM7 and MCM3 proteins, so some of them participate in cell cycle regulation. MCM2 is localized in the nucleus throughout interphase. It is required for entry into the S phase and cell division. Anti-MCM2 labels proliferating cells in normal and tumor tissue. MCM2 has been Host Rabbit Application Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat, Monkey -
MCM2 [MD32R]
Description Minichromosome maintenance protein 2 (MCM2), also known as DNA replication licensing factor MCM2, is a member of the MCM family that regulates mammalian DNA replication. This family is composed of six related subunits, called the hexameric MCM2-7 complex, that are conserved in all eukaryotes. It functions as a replicative helicase, the molecular motor that both unwinds duplex DNA and powers fork progression during DNA replication. MCM2 acts as a factor to license DNA for one and only one round of replication per cell cycle. In the cell cycle, levels of the MCM family gradually increase in a variable manner from G0 into the G1/S phase. In the G0 stage, the amounts of MCM2 and MCM5 proteins are much lower than that of MCM7 and MCM3 proteins, so some of them participate in cell cycle regulation. MCM2 is localized in the nucleus throughout interphase. It is required for entry into the S phase and cell division. Anti-MCM2 labels proliferating cells in normal and tumor tissue. MCM2 has been Host Rabbit Application Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat, Monkey -
NF-κB p65 [MD35R]
Description Transcription factors of the nuclear factor κ B (NF-κB)/Rel family play a pivotal role in inflammatory and immune responses. There are five family members in mammals: RelA, c-Rel, RelB, NF-κB1 (p105/p50), and NF-κB2 (p100/p52). Both p105 and p100 are proteolytically processed by the proteasome to produce p50 and p52, respectively. Rel proteins bind p50 and p52 to form dimeric complexes that bind DNA and regulate transcription. In unstimulated cells, NF-κB is sequestered in the cytoplasm by IκB inhibitory proteins. NF-κB-activating agents can induce the phosphorylation of IκB proteins, targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression. NIK and IKKα (IKK1) regulate the phosphorylation and processing of NF-κB2 (p100) to produce p52, which is then translocated to the nucleus. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat, Hamster, Monkey, Dog -
NF-κB p65 [MD35R]
Description Transcription factors of the nuclear factor κ B (NF-κB)/Rel family play a pivotal role in inflammatory and immune responses. There are five family members in mammals: RelA, c-Rel, RelB, NF-κB1 (p105/p50), and NF-κB2 (p100/p52). Both p105 and p100 are proteolytically processed by the proteasome to produce p50 and p52, respectively. Rel proteins bind p50 and p52 to form dimeric complexes that bind DNA and regulate transcription. In unstimulated cells, NF-κB is sequestered in the cytoplasm by IκB inhibitory proteins. NF-κB-activating agents can induce the phosphorylation of IκB proteins, targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression. NIK and IKKα (IKK1) regulate the phosphorylation and processing of NF-κB2 (p100) to produce p52, which is then translocated to the nucleus. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat, Hamster, Monkey, Dog