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CTNNB1 antibody
Description Mouse monoclonal CTNNB1 antibody (Shipping Cost: €205.00) Host Mouse Application Flow Cytometry (FC),Immunofluorescence (IF),Western Blot (WB) Reactivity Human,Dog (Canine) Concentration 500 ug-1 mg/ml -
GAS7 antibody
Description Mouse monoclonal GAS7 antibody (Shipping Cost: €205.00) Host Mouse Application Flow Cytometry (FC),Immunofluorescence (IF),Immunohistochemistry (IHC),Western Blot (WB) Reactivity Human,Dog (Canine),Rat Concentration 500 ug-1 mg/ml -
OSBPL11 antibody
Description Mouse monoclonal OSBPL11 antibody (Shipping Cost: €205.00) Host Mouse Application Immunofluorescence (IF),Western Blot (WB) Reactivity Human Concentration 500 ug-1 mg/ml -
OTUB2 antibody
Description Mouse monoclonal OTUB2 antibody (Shipping Cost: €205.00) Host Mouse Application Immunofluorescence (IF),Western Blot (WB) Reactivity Human Concentration 500 ug-1 mg/ml -
TUBAL3 antibody
Description Mouse monoclonal TUBAL3 antibody (Shipping Cost: €205.00) Host Mouse Application Flow Cytometry (FC),Immunofluorescence (IF),Immunohistochemistry (IHC),Western Blot (WB) Reactivity Human Concentration 500 ug-1 mg/ml -
UBXN10 antibody
Description Mouse monoclonal UBXN10 antibody (Shipping Cost: €205.00) Host Mouse Application Flow Cytometry (FC),Immunofluorescence (IF),Western Blot (WB) Reactivity Human Concentration 500 ug-1 mg/ml -
ACTH [2F6]
Description ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).ĀIt also may react with other tumors (e.g. some small cell carcinomas of the lung) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse, Rat -
ACTH [2F6]
Description ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).ĀIt also may react with other tumors (e.g. some small cell carcinomas of the lung) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse, Rat -
MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1) [2F6]
Description Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli, including growth factors. The MEK kinases (also designated MAP kinase kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and p38. These activated MEKs in turn phosphorylate and activate the MAP kinases. The MEK kinases include Raf-1, Raf-B, Mos, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4 and ASK 1 (MEK kinase- 5). MEK kinase-1 activates the ERK and c-Jun NH2-terminal kinase (JNK) pathways by phosphorylation of MAP2K1 and MAP2K4, and also activates the central protein kinases of the NFĪŗB pathway, CHUK and IKBKB. Additionally, MEK kinase-1 uses an E3 ligase through its PHD domain, a RING-finger-like structure, to target proteins for degradation through ubiquitination. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human