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Tumor Necrosis Factor a (TNFa)
Host Mouse Application ELISA,Western Blot (WB),Radioimmunoassay (RIA) Reactivity Human Alternative names Human Tumor Necrosis Factor a -
Tyrosine Kinase (Geodia cydonium)
Host Mouse Application ELISA,Western Blot (WB),Immunohistochemistry (IHC),Immunoprecipitation (IP) Alternative names receptor Tyrosine Kinase (Geodia cydonium) -
Tyrosine Kinase (Geodia cydonium)
Host Mouse Application ELISA,Western Blot (WB),Immunohistochemistry (IHC),Immunoprecipitation (IP) Alternative names receptor Tyrosine Kinase (Geodia cydonium) -
Uroguanylin / Guanylate Cyclase Activator 2B
Host Rabbit Application ELISA,Western Blot (WB),Immunohistochemistry (IHC),Radioimmunoassay (RIA) Reactivity Human Alternative names Human Uroguanylin, circulating form (aa 1-8) -
Uroguanylin / Guanylate Cyclase Activator 2B
Host Rabbit Application ELISA,Western Blot (WB),Immunohistochemistry (IHC),Radioimmunoassay (RIA) Reactivity Human Alternative names Human Uroguanylin, circulating form (aa 1-8) -
ABCB4/MDR3 Polyclonal
Description Mediates ATP-dependent export of organic anions and drugs from the cytoplasm. Hydrolyzes ATP with low efficiency. Human MDR3 is not capable of conferring drug resistance. Mediates the translocation of phosphatidylcholine across the canalicular membrane of the hepatocyte. Defects in ABCB4 are the cause of progressive familial intrahepatic cholestasis type 3 (PFIC3). PFIC3 is an autosomal recessive liver disorder presenting with early onset cholestasis that progresses to cirrhosis and liver failure before adulthood. It is characterized by elevated serum gamma-glutamyltransferase levels. Defects in ABCB4 are a cause of intrahepatic cholestasis of pregnancy (ICP); also known as obstetric cholestasis. ICP is a multifactorial liver disorder of pregnancy. It presents during the second or, more commonly, the third trimestre of pregnancy with intense pruritus which becomes more severe with advancing gestation and cholestasis. Cholestasis results from abnormal biliary transport from the liver in Host Rabbit Application ELISA, Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse -
ABCB4/MDR3 Polyclonal
Description Mediates ATP-dependent export of organic anions and drugs from the cytoplasm. Hydrolyzes ATP with low efficiency. Human MDR3 is not capable of conferring drug resistance. Mediates the translocation of phosphatidylcholine across the canalicular membrane of the hepatocyte. Defects in ABCB4 are the cause of progressive familial intrahepatic cholestasis type 3 (PFIC3). PFIC3 is an autosomal recessive liver disorder presenting with early onset cholestasis that progresses to cirrhosis and liver failure before adulthood. It is characterized by elevated serum gamma-glutamyltransferase levels. Defects in ABCB4 are a cause of intrahepatic cholestasis of pregnancy (ICP); also known as obstetric cholestasis. ICP is a multifactorial liver disorder of pregnancy. It presents during the second or, more commonly, the third trimestre of pregnancy with intense pruritus which becomes more severe with advancing gestation and cholestasis. Cholestasis results from abnormal biliary transport from the liver in Host Rabbit Application ELISA, Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse -
ABCG2/BCRP/CD338 [B1]
Description Breast Cancer Resistance Protein (BCRP) is a 70 kDa ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human -
Actin Smooth Muscle (SMA) [1A4]
Description This antibody recognizes actin isotypes alpha of smooth muscle and those cells with myofibroblast differentiation. It labels smooth muscular cells, myofibroblasts, and myoepithelial cells. Using this antibody with other myogenic markers such as muscle actin, desmin and vimentin will be very helpful for differentiation of tumor from muscle origin. It is a useful marker for the identification leiomyosarcomas. It is a useful marker for distinct ion benign proliferative lesions of the breast from neoplastic proliferations. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human -
Adipolin/Fam132a/C1qdc2/CTRP12 Polyclonal
Description Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes. Adipose tissue secretes various bioactive molecules, referred to as adipokines, whose dysregulation can mediate changes in glucose homeostasis and inflammatory responses. Adipolin or C1qdc2/CTRP12 is an insulin-sensitizing adipokine that is abundantly expressed by fat tissues and designate this adipokine as adipolin (adipose-derived insulin-sensitizing factor). Adipolin expression in adipose tissue and plasma was reduced in obesity. Systemic administration of adipolin ameliorated glucose intolerance and insulin resistance in dietinduced obese mice. Adipolin administration also reduced macrophage accumulation and proinflammatory gene expression in the adipose tissue of obesity. Studies suggest that adipolin functions as an anti-inflammatory adipokine that exerts beneficial actions on glucose metabolism. Therefore, adipolin represents a new target molecule for the treatment of insulin resistanc Host Rabbit Application ELISA, Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat, Bovine, Dog (Canine), Horse,Pig (Porcine), Sheep