CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

You are here

Products

back to search results

Synuclein Alpha [MD23R]

Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: MD23R
Host: Rabbit
Isotype: IgG
Application: Immunohistochemistry (IHC)
Application notes: 25-50
Conjugation Type: Unconjugated
Reactivity: Human, Mouse, Rat
General notes: Localization: cytoplasm, membrane, nucleus.
Buffer: citrate pH6.0 or EDTA pH8.0
UNSPSC code: 12352203

Alpha-Synuclein is the major component of Lewy bodies and Lewy neuritis in sporadic Parkinson disease. Alpha-Synuclein is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals. The deposition of the abundant presynaptic brain protein alpha-synuclein as fibrillary aggregates in neurons or glial cells is a hallmark lesion in a subset of neurodegenerative disorders. These disorders include Parkinson's disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy, collectively referred to as synucleinopathies. Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive accumulation in selected neurons of protein inclusions containing alpha-synuclein and ubiquitin. (Shipping Cost: €200.00)

Synuclein Alpha [MD23R]

Alpha-Synuclein is the major component of Lewy bodies and Lewy neuritis in sporadic Parkinson disease. Alpha-Synuclein is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals. The deposition of the abundant presynaptic brain protein alpha-synuclein as fibrillary aggregates in neurons or glial cells is a hallmark lesion in a subset of neurodegenerative disorders. These disorders include Parkinson's disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy, collectively referred to as synucleinopathies. Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive accumulation in selected neurons of protein inclusions containing alpha-synuclein and ubiquitin.