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Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) [3D3]

Product information References Bioinformatics Documents
Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: 3D3
Host: Mouse
Isotype: IgG1
Application: Immunohistochemistry (IHC), Flow cytometry (FC), Immunofluorescence (IF), Western Blot (WB)
Application notes: 50-200
Conjugation Type: Unconjugated
Reactivity: Human, Rabbit, Rat
General notes: Localization: cytoplasm, some membrane.
Buffer: citrate pH6.0 or EDTA pH8.0
UNSPSC code: 12352203

Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology. (Shipping Cost: €200.00)

Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) [3D3]

Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.