You are here
Products
Parathyroid Hormone (N-Terminal) (PTH) [3H9]
Product group: | Primary |
Monoclonal/ Polyclonal: | Monoclonal |
Clone: | 3H9 |
Host: | Mouse |
Isotype: | IgG2b |
Application: | Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) |
Application notes: | Prediluted |
Conjugation Type: | Unconjugated |
Lightchain type: | Kappa |
Reactivity: | Human |
Predicted to react with: | Mouse, Rat, Rabbit, Cow, Dog, Pig, Deer, Orangutan |
General notes: | Localization: cytoplasm, secreted. |
Buffer: | citrate pH6.0 |
UNSPSC code: | 12352203 |
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. (Shipping Cost: €200.00)
Parathyroid Hormone (N-Terminal) (PTH) [3H9]
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Alternative names: