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p34/CDC2/CDK1 [POH-1]
Product group: | Primary |
Monoclonal/ Polyclonal: | Monoclonal |
Clone: | POH-1 same as cdc2.1 |
Host: | Mouse |
Isotype: | IgG2a |
Application: | Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) |
Application notes: | 25-100 |
Conjugation Type: | Unconjugated |
Reactivity: | Human, Bovine, Monkey |
General notes: | Localization: nucleus, cytoplasm. |
Buffer: | citrate pH6.0 |
UNSPSC code: | 12352203 |
p34cdc2 is a phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the cell cycle. It is the catalytic subunit of the maturation-promoting factor (MPF) and complexes with both cyclin A and B in mammalian cells. Activated p34cdc2 kinase phosphorylates a variety of substrates leading to some specific events of mitosis including nuclear envelope break-down and chromosome condensation. p34cdc2 has also been implicated in lymphoid proliferation. (Shipping Cost: €200.00)
p34/CDC2/CDK1 [POH-1 same as cdc2.1]
p34cdc2 is a phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the cell cycle. It is the catalytic subunit of the maturation-promoting factor (MPF) and complexes with both cyclin A and B in mammalian cells. Activated p34cdc2 kinase phosphorylates a variety of substrates leading to some specific events of mitosis including nuclear envelope break-down and chromosome condensation. p34cdc2 has also been implicated in lymphoid proliferation.
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