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NUT/NUTM1 Polyclonal

Product information References Bioinformatics Documents
Product group: Primary
Monoclonal/ Polyclonal: Polyclonal
Host: Rabbit
Isotype: IgG
Application: ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC)
Application notes: 25-100
Conjugation Type: Unconjugated
Reactivity: Human
General notes: Localization: cytoplasm, nucleus.
Buffer: citrate pH6.0 or EDTA pH8.0
UNSPSC code: 12352203

NUT is known to fuse with BRD3 and BRD4 in NUT midline carcinoma (NMC), a rare and aggressive human cancer. In the majority of NMCs (~75%), most of the coding sequence is fused with BRD4 creating chimeric genes that encode BRD-NUT fusion proteins. In other cases, it fuses with BRD3 or an unknown partner gene. This tumor is often termed NUT-variant. To date, NMCs are still frequently undiagnosed or misdiagnosed and there are no effective treatment options. (Shipping Cost: €200.00)

NUT Polyclonal

NUT is known to fuse with BRD3 and BRD4 in NUT midline carcinoma (NMC), a rare and aggressive human cancer. In the majority of NMCs (~75%), most of the coding sequence is fused with BRD4 creating chimeric genes that encode BRD-NUT fusion proteins. In other cases, it fuses with BRD3 or an unknown partner gene. This tumor is often termed NUT-variant. To date, NMCs are still frequently undiagnosed or misdiagnosed and there are no effective treatment options.