CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

You are here

Products

back to search results

Neurofilament [NF421]

Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: NF421
Host: Mouse
Isotype: IgG1
Application: Flow cytometry (FC), Immunohistochemistry (IHC)
Application notes: 100-300
Conjugation Type: Unconjugated
Reactivity: Human, Mouse, Rat,Pig (Porcine), Chicken
General notes: Localization: cytoplasm.
UNSPSC code: 12352203

Neuofilaments (NF) are members of the intermediate filament protein family. These neuron-specific filaments are the major constituents of the axonal cytoskeleton . NFs are composed of three major proteins: NF-H is the heavy molecular weight protein (200 kDa), NF-M the medium (160 kDa) and NF-L the light protein (68kDa). The NF-L and NF-M mRNAs are detected early in the embryonal brain, with a progressive increase in their levels during development, while the NF-H mRNA is barely detectable at embryonal stages but accumulates later in the postnatal brain. This antibody labels neurons of the central and peripheral nervous system, and is a useful for the identification of tumors with neuronal differentiation (Shipping Cost: €200.00)

Neurofilament [NF421]

Neuofilaments (NF) are members of the intermediate filament protein family. These neuron-specific filaments are the major constituents of the axonal cytoskeleton . NFs are composed of three major proteins: NF-H is the heavy molecular weight protein (200 kDa), NF-M the medium (160 kDa) and NF-L the light protein (68kDa). The NF-L and NF-M mRNAs are detected early in the embryonal brain, with a progressive increase in their levels during development, while the NF-H mRNA is barely detectable at embryonal stages but accumulates later in the postnatal brain. This antibody labels neurons of the central and peripheral nervous system, and is a useful for the identification of tumors with neuronal differentiation