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MNDA Polyclonal

Product group: Primary
Monoclonal/ Polyclonal: Polyclonal
Host: Rabbit
Isotype: IgG
Application: Immunohistochemistry (IHC), Western Blot (WB)
Application notes: 25-100
Conjugation Type: Unconjugated
Reactivity: Human
General notes: Localization: nucleus, cytoplasm.
Buffer: citrate pH6.0 or EDTA pH8.0
UNSPSC code: 12352203

Myeloid cell nuclear differentiation antigen or MNDA is expressed constitutively in cells of the myeloid lineage. Found in promyelocyte stage cells as well as in all other stage cells including peripheral blood monocytes and granulocytes. Also appear in myeloblast cells in some cases of acute myeloid Leukemia. May act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1. (Shipping Cost: €200.00)

MNDA Polyclonal

Myeloid cell nuclear differentiation antigen or MNDA is expressed constitutively in cells of the myeloid lineage. Found in promyelocyte stage cells as well as in all other stage cells including peripheral blood monocytes and granulocytes. Also appear in myeloblast cells in some cases of acute myeloid Leukemia. May act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1.