Metapneumovirus is a discovered paramyxovirus of the subfamily Pneumovirinae, which also includes avian pneumovirus and human respiratory syncytial virus (HRSV). Human metapneumovirus (HMPV) is classified as a member of the family Pneumoviridae, which comprises large enveloped negative-sense RNA viruses. This taxon was formerly a subfamily within the Paramyxoviridae family but was reclassified in 2016 as a separate family with two genera, Metapneumovirus (which includes HMPV) and Orthopneumovirus (which includes respiratory syncytial virus). HMPV is an enveloped virus with a nonsegmented negative-sense RNA genome. HMPV is most closely related phylogenetically to avian metapneumovirus (APV). The complete genome sequence reveals a high level of homology with APV. Phylogenetic analysis has identified two subgroups of HMPV, subgroups A and B, and two clades within each of these subgroups (designated A1, A2, B1, and B2), which often circulate concurrently. A study of 727 Australian HMPV iso

TSH (Thyroid Stimulating Hormone) [TSH220]

TSH is a member of the glycoprotein hormone family, constituting a subset of the cystine-knot growth factor superfamily. TSH is produced by the pituitary thyrotrophs and released into circulation in a pulsatile manner. It stimulates thyroid functions using a specific membrane TSH receptor (TSHR) that belongs to the superfamily of G protein-coupled receptors (GPCRs). TSH beta is the beta subunit of thyroid stimulating hormone. This TSH antibody labels normal and neoplastic thyrotropic cells. It may be useful in classification of pituitary tumors.

TSH (Thyroid Stimulating Hormone) [TSH220]