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MDR1/ABCB1/P-Glycoprotein [D-11]

Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: D-11
Host: Mouse
Isotype: IgG2b
Application: Immunohistochemistry (IHC)
Application notes: 50-250
Conjugation Type: Unconjugated
Reactivity: Human
General notes: Localization: cytoplasm, membrane.
Buffer: citrate pH6.0
UNSPSC code: 12352203

Multi-Drug Resistance Marker (P-Glycoprotein) is a 170 kD cell membrane protein of the multi-drug resistance gene, MDR-1. Studies have linked the presence of P-Glycoprotein with resistance to a wide variety of chemotherapeutic agents. P-Glycoprotein is also found in various concentrations in most normal tissues, suggesting that the primary role for this protein is in normal secretion of physiological metabolites. (Shipping Cost: €200.00)

MDR1/ABCB1/P-Glycoprotein [D-11]

Multi-Drug Resistance Marker (P-Glycoprotein) is a 170 kD cell membrane protein of the multi-drug resistance gene, MDR-1. Studies have linked the presence of P-Glycoprotein with resistance to a wide variety of chemotherapeutic agents. P-Glycoprotein is also found in various concentrations in most normal tissues, suggesting that the primary role for this protein is in normal secretion of physiological metabolites.