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MDR1/ABCB1/P-Glycoprotein [D-11]
Product group: | Primary |
Monoclonal/ Polyclonal: | Monoclonal |
Clone: | D-11 |
Host: | Mouse |
Isotype: | IgG2b |
Application: | Immunohistochemistry (IHC) |
Application notes: | 50-250 |
Conjugation Type: | Unconjugated |
Reactivity: | Human |
General notes: | Localization: cytoplasm, membrane. |
Buffer: | citrate pH6.0 |
UNSPSC code: | 12352203 |
Multi-Drug Resistance Marker (P-Glycoprotein) is a 170 kD cell membrane protein of the multi-drug resistance gene, MDR-1. Studies have linked the presence of P-Glycoprotein with resistance to a wide variety of chemotherapeutic agents. P-Glycoprotein is also found in various concentrations in most normal tissues, suggesting that the primary role for this protein is in normal secretion of physiological metabolites. (Shipping Cost: €200.00)
MDR1/ABCB1/P-Glycoprotein [D-11]
Multi-Drug Resistance Marker (P-Glycoprotein) is a 170 kD cell membrane protein of the multi-drug resistance gene, MDR-1. Studies have linked the presence of P-Glycoprotein with resistance to a wide variety of chemotherapeutic agents. P-Glycoprotein is also found in various concentrations in most normal tissues, suggesting that the primary role for this protein is in normal secretion of physiological metabolites.
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