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Glut1 [EP141]

Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: EP141
Host: Rabbit
Isotype: IgG
Application: Immunohistochemistry (IHC)
Application notes: Prediluted
Conjugation Type: Unconjugated
Reactivity: Human
General notes: Localization: membrane.
Buffer: citrate pH6.0 or EDTA pH8.0
UNSPSC code: 12352203

Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1, also known as SCL2A1, is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung , bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiatiation of malignant mesothelioma (positive) from reactive mesothelium (negative). (Shipping Cost: €200.00)

Glut1 [EP141]

Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1, also known as SCL2A1, is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung , bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiatiation of malignant mesothelioma (positive) from reactive mesothelium (negative).