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Fibromodulin/FMOD [H11]

Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: H11
Host: Mouse
Isotype: IgG2b
Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application notes: 50-200
Conjugation Type: Unconjugated
Lightchain type: Kappa
Reactivity: Human, Mouse, Rat
General notes: Localization: membrane, cytoplasm.
Buffer: citrate pH6.0 or EDTA pH8.0
UNSPSC code: 12352203

Small leucine-rich proteoglycans (SLRPs), such as Decorin, Biglycan, Fibromodulin and Lumican, mediate extracellular matrix organization and are binding partners of TGFβ. Fibromodulin is a collagen-binding Keratan sulphate proteoglycan that influences adhesion processes of connective tissue and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness. The core proteins of SLRPs consist of a central region of leucine-rich repeats flanked by disulfide-linkages of the terminal domains. Fibromodulin is a ubiquitous protein that is most prominent in articular cartilage, tendon and ligament. The human Fibromodulin gene maps to chromosome 1q32.1 and encodes a 376 amino acid protein. (Shipping Cost: €200.00)

Fibromodulin/FMOD [H11]

Small leucine-rich proteoglycans (SLRPs), such as Decorin, Biglycan, Fibromodulin and Lumican, mediate extracellular matrix organization and are binding partners of TGFβ. Fibromodulin is a collagen-binding Keratan sulphate proteoglycan that influences adhesion processes of connective tissue and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness. The core proteins of SLRPs consist of a central region of leucine-rich repeats flanked by disulfide-linkages of the terminal domains. Fibromodulin is a ubiquitous protein that is most prominent in articular cartilage, tendon and ligament. The human Fibromodulin gene maps to chromosome 1q32.1 and encodes a 376 amino acid protein.