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CD71 (Transferrin Receptor) [TFRC/1817]

Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: TFRC/1817
Host: Mouse
Isotype: IgG2b
Application: ELISA, Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC)
Application notes: Prediluted
Conjugation Type: Unconjugated
Lightchain type: Kappa
Reactivity: Human
General notes: Localization: membrane.
Buffer: Tris EDTA pH9.0
UNSPSC code: 12352203

CD71, the transferrin receptor, is a type II trans-membrane homodimer glycoprotein (180 kDa) involved in the cellular uptake of iron via internalization of iron-loaded transferring. CD71 is highly expressed in immature erythroid cells, placental tissue and rapidly dividing cells. Loss of CD71 is observed in mature erythrocytes. Over expression of CD71 has also been described for various types of cancers including lung, colon, breast and pancreas. CD71 antibody is useful in identifying erythroid precursors. (Shipping Cost: €200.00)

CD71 (Transferrin Receptor) [TFRC/1817]

CD71, the transferrin receptor, is a type II trans-membrane homodimer glycoprotein (180 kDa) involved in the cellular uptake of iron via internalization of iron-loaded transferring. CD71 is highly expressed in immature erythroid cells, placental tissue and rapidly dividing cells. Loss of CD71 is observed in mature erythrocytes. Over expression of CD71 has also been described for various types of cancers including lung, colon, breast and pancreas. CD71 antibody is useful in identifying erythroid precursors.