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Tyrosinase-Related Protein-1 (TYRP-1) [SPM611]
| Product group: | Primary |
| Monoclonal/ Polyclonal: | Monoclonal |
| Clone: | SPM611 |
| Host: | Mouse |
| Isotype: | IgG2a |
| Application: | Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) |
| Application notes: | 25-100 |
| Conjugation Type: | Unconjugated |
| Lightchain type: | Kappa |
| Reactivity: | Human, Mouse |
| General notes: | Localization: cytoplasm. |
| Buffer: | EDTA pH8.0 |
| UNSPSC code: | 12352203 |
It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TYRP-1). It is involved in melanin synthesis. TYRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.ĀRecent evidence suggests that TYRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TYRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. (Shipping Cost: €200.00)
Tyrosinase-Related Protein-1 (TYRP-1) [SPM611]
It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TYRP-1). It is involved in melanin synthesis. TYRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.ĀRecent evidence suggests that TYRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TYRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
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